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Recruiting NCT06832436

NCT06832436 Atrial Strain in Septic Shock

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Clinical Trial Summary
NCT ID NCT06832436
Status Recruiting
Phase
Sponsor Centre Hospitalier Universitaire, Amiens
Condition Septic Shock
Study Type OBSERVATIONAL
Enrollment 60 participants
Start Date 2025-03-06
Primary Completion 2026-09

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 60 participants in total. It began in 2025-03-06 with a primary completion date of 2026-09.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Septic shock is a critical condition associated with high mortality. Transthoracic echocardiography is widely used to evaluate cardiac function and guide treatment. Left and right atrial strain (LAS and RAS) measured via speckle tracking echocardiography have shown prognostic value in cardiovascular diseases. However, differences exist between echocardiographic software, leading to challenges in result comparability. This study aims to compare LAS and RAS measurements between ECHOPAC and UWS software, evaluate AutoStrain technology, and assess reproducibility across observers. The study is non-interventional and will use retrospective echocardiographic data from patients treated for septic shock. The findings will contribute to improving measurement standardization in critically ill patients.

Eligibility Criteria

Inclusion Criteria: * Age: \>18 years * Adult patients admitted to critical care for septic shock (SEPSIS-3 definition) * TTE performed as part of medical management * No objection to data usage Exclusion Criteria: * Pregnancy * Moderate to severe valvular regurgitation/stenosis (\>grade 2) * Ventricular or supraventricular tachyarrhythmia (HR \>140 bpm) at the time of TTE * Poor echogenicity preventing LAS measurement * Mechanical circulatory support * Pacemaker dependence * Patients under guardianship

Contact & Investigator

Central Contact

Christophe Beyls, MD

✉ beyls.christophe@chu-amiens.fr

📞 33+322087866

Frequently Asked Questions

Who can join the NCT06832436 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Septic Shock. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06832436 currently recruiting?

Yes, NCT06832436 is actively recruiting participants. Contact the research team at beyls.christophe@chu-amiens.fr for enrollment information.

Where is the NCT06832436 trial being conducted?

This trial is being conducted at Salouël, France.

Who is sponsoring the NCT06832436 clinical trial?

NCT06832436 is sponsored by Centre Hospitalier Universitaire, Amiens. The trial plans to enroll 60 participants.

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