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Recruiting NCT06248359
Association Between Postoperative Administration of L-Arginine and CSA-AKI
Trial Parameters
Condition Acute Kidney Injury
Sponsor Xijing Hospital
Study Type OBSERVATIONAL
Phase N/A
Enrollment 7,000
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2023-12-01
Completion 2025-12-01
Interventions
L-Arginine hydrochloride
Brief Summary
To investigate the association between the the early administration of L-Arginine after CPB-assisted cardiac surgery and the incidence of CS-AKI in adult patients. To test if it can reduce the incidence of post-operative AKI.
Eligibility Criteria
Inclusion Criteria: * adult patients (over 18 years) * underwent CPB assisted cardiac surgery * admitted to ICU Exclusion Criteria: * congenital heart disease * underwent deep hypothermic circulatory arrest (DHCA) * with glomerular filtration rate (eGFR) below 30 mL/min/1.73 m²