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Recruiting NCT06898294

Assessment of Kidney Function by Electrical Impedance Tomography (EIT)

Trial Parameters

Condition Chronic Kidney Diseases
Sponsor The University of Hong Kong
Study Type OBSERVATIONAL
Phase N/A
Enrollment 144
Sex ALL
Min Age 18 Years
Max Age 90 Years
Start Date 2021-09-01
Completion 2025-08-31
Interventions
EIT kidney function assessment

Brief Summary

The product under investigation is named Gense EIT-kidney device. This kidney device is a portable and non-invasive imaging modality capable of capturing the cross-sectional bioelectrical impedance distribution of the kidney at multiple current injection frequencies using electrical impedance tomography (EIT). Currently, the kidney device employs a band consisting of 16 equally distributed electrodes around the abdomen. The electrode band is connected to a control unit that switches the electrode stimulation and measurement pairs, then sends the collected measurement to a computational unit for image reconstruction. The images are then post-processed to extract functional kidney images for diagnosis. This kidney device can connect to an external screen, allowing the functional images to be produced and visualized.

Eligibility Criteria

Inclusion Criteria: \- clinically diagnosed with CKD at different stages (stage 1-5) of the disease based on GFR measurement results Age: 18-90. Gender: Male/ Female Exclusion Criteria: * ● Subjects with known kidney disease or abnormalities (for the control group). * Subjects who had any kind of kidney surgery or kidney transplantation. * Subjects with damaged skin on the abdomen. * Subjects with implanted electronic devices. * Subjects with spinal diseases/discomfort * Subjects who had any recent abdominal surgery * Pregnant women. * Obese subjects (BMI\>35). * Subjects with uncontrollable involuntary body movements such as degenerative disorders (e.g., Alzheimer's and Parkinson's disease); Seizure disorders (e.g., epilepsy, stroke, neuroleptic drugs); Neurological disorders (e.g., tardive dyskinesia and cerebral palsy, tremors, myoclonus, tics, athetosis, etc.)

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