NCT04578769 Assessment of Different Modified POEM for Achalasia
| NCT ID | NCT04578769 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Peking Union Medical College Hospital |
| Condition | Esophageal Achalasia |
| Study Type | INTERVENTIONAL |
| Enrollment | 52 participants |
| Start Date | 2020-09-02 |
| Primary Completion | 2025-12-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 52 participants in total. It began in 2020-09-02 with a primary completion date of 2025-12-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The aims of this study is to compare the efficacy and safety of conventional myotomy (circular myotomy) and modified myotomy (full-thickness myotomy) in the treatment of achalasia patients.
Eligibility Criteria
Inclusion Criteria: * diagnosed as achalasia type I or II according to the Chicago Classification Version 4.0, with an Eckardt score \>3 * Their age is ≥14years and ≤70 years * Able to give written consent Exclusion Criteria: * undergone previous surgical treatments * had contra-indication to general anesthesia * previous surgery of the mediastinum, stomach, or esophagus; * Pregnant or lactating female * type III achalasia * current alcohol or drug addiction, mental retardation, severe congenital or acquired coagulopathy (international normalized ratio \>1.6) * hepatic cirrhosis with or without portal hypertension, eosinophilic esophagitis (biopsies were performed at index endoscopy), or confirmed Barrett's esophagus * esophageal diverticula or hiatal hernia based on findings from the index barium esophagram, or other conditions that the investigator believed not appropriate for POEM procedure
Contact & Investigator
Tao Guo, MD
PRINCIPAL INVESTIGATOR
Peking Union Medical College Hospital
Frequently Asked Questions
Who can join the NCT04578769 clinical trial?
This trial is open to participants of all sexes, aged 14 Years or older, up to 70 Years, studying Esophageal Achalasia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04578769 currently recruiting?
Yes, NCT04578769 is actively recruiting participants. Contact the research team at guoqiong990@126.com for enrollment information.
Where is the NCT04578769 trial being conducted?
This trial is being conducted at Beijing, China.
Who is sponsoring the NCT04578769 clinical trial?
NCT04578769 is sponsored by Peking Union Medical College Hospital. The principal investigator is Tao Guo, MD at Peking Union Medical College Hospital. The trial plans to enroll 52 participants.