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Medical Condition

esophageal achalasia

Total Trials
4
Recruiting Now
4
Trial Phases
Phase 2, Phase 3

ClinicalMetric tracks all active clinical trials for esophageal achalasia sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — esophageal achalasia Clinical Trials

How many clinical trials are currently recruiting for esophageal achalasia?
ClinicalMetric currently tracks 4 actively recruiting clinical trials for esophageal achalasia, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 4. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for esophageal achalasia?
esophageal achalasia research spans Phase 2 (1 trial), Phase 3 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a esophageal achalasia clinical trial?
Eligibility criteria for esophageal achalasia trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 2
1
Phase 3
1
Top Sponsors
University Hospital, Bordeaux 1 trial
The Cleveland Clinic 1 trial
Centre Hospitalier Universitaire de Nīmes 1 trial
Medical University of Vienna 1 trial

Recruiting Clinical Trials

NCT06230536
Recruiting
MARIMPACH : Contribution of High-resolution Manometry With Impedancemetry for the Evaluation of Esophageal Clearance in Achalasia
Enrollment
104 pts
Location
France
Sponsor
University Hospital, Bordeaux
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NCT06721520 Phase 2, Phase 3
Recruiting
Effectiveness of Methods for Pyloric Drainage in esophagecTomY: Botox vs. Pyloromyotomy
Enrollment
170 pts
Location
United States
Sponsor
The Cleveland Clinic
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NCT05899842
Recruiting
Routine Versus Symptomatic Protein Pump Inhibitor Therapy for Prevention of Gastroesophageal Reflux After Per Oral Endoscopic Myotomy for Esophageal Achalasia
Enrollment
132 pts
Location
France
Sponsor
Centre Hospitalier Universitai...
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NCT02518542
Recruiting
Per Oral Endoscopic Myotomy (POEM) and Prolonged Dilatation (PRD) for Achalasia
Enrollment
400 pts
Location
Austria
Sponsor
Medical University of Vienna
View Trial →

Related Conditions

esophageal cancer surgery (1) esophagectomy (1) delayed gastric emptying following procedure (1) esophageal diseases (1) pylorus dysfunction (1) esophageal dysmotility (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: November 2026  ·  Data Methodology