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Recruiting NCT06221800

NCT06221800 Assess Diversity of Gut Microbiome in Met NSCLC in Correlation to Tx & Adverse Effects

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Clinical Trial Summary
NCT ID NCT06221800
Status Recruiting
Phase
Sponsor University of California, Irvine
Condition Non Small Cell Lung Cancer
Study Type OBSERVATIONAL
Enrollment 82 participants
Start Date 2024-01-31
Primary Completion 2026-12

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL
Interventions
Microbiome

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 82 participants in total. It began in 2024-01-31 with a primary completion date of 2026-12.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This is a pilot study collecting data on the diversity and composition of gut microbiomes in subjects with advanced/metastatic Non-Small Cell Lung Cancer (NSCLC) while receiving treatment for NSCLC.

Eligibility Criteria

Inclusion Criteria: * 1\. Advanced/Metastatic non-small cell lung cancer NSCLC patients. * 2\. The patient himself/herself must be 18 years of age on day of signing informed consent. * 3\. The subject has signed the informed consent form. * 4\. The patient must be eligible to receive FDA approved and non-approved PD1 inhibitors (i.e. pembrolizumab, nivolumab) or PDL1 inhibitor (i.e. atezolizumab, durvalumab) either single agent or as combination therapy with chemotherapy, or be eligible to receive FDA approved and non-approved tyrosine kinase inhibitors. * 5\. The subject will be registered upon submission of the samples. When submitted on separate dates, the submission occurring later will be considered the date of registration Exclusion Criteria: * 1\. Those subjects who are determined clinically unstable of the participation of this study as determined by the PI or treating physician will be excluded and asked to focus on their treatment.

Contact & Investigator

Central Contact

Chao Family Comprehensive Cancer Center University of California, Irvine

✉ ucstudy@uci.edu

📞 1-877-827-8839

Principal Investigator

Misako Nagasaka, MD,PhD

PRINCIPAL INVESTIGATOR

Chao Family Comprehensive Cancer Center

Frequently Asked Questions

Who can join the NCT06221800 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Non Small Cell Lung Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06221800 currently recruiting?

Yes, NCT06221800 is actively recruiting participants. Contact the research team at ucstudy@uci.edu for enrollment information.

Where is the NCT06221800 trial being conducted?

This trial is being conducted at Orange, United States.

Who is sponsoring the NCT06221800 clinical trial?

NCT06221800 is sponsored by University of California, Irvine. The principal investigator is Misako Nagasaka, MD,PhD at Chao Family Comprehensive Cancer Center. The trial plans to enroll 82 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology