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Recruiting NCT04427163
Assesment of Multiomics Profiles in Health and Disease.
Trial Parameters
Condition Genetic Predisposition to Disease
Sponsor The Institute of Molecular and Translational Medicine, Czech Republic
Study Type OBSERVATIONAL
Phase N/A
Enrollment 1,100
Sex ALL
Min Age 18 Years
Max Age 68 Years
Start Date 2018-09-01
Completion 2028-09-01
Interventions
Blood sample analysisHealth statusRace and ethnicity
Brief Summary
This study will determine reference genomic, transcriptomic, proteomic and metabolomic profiles in Czech population and will evaluate its correlation with the disease phenotype.
Eligibility Criteria
Inclusion Criteria: * age 18 - 68 years * (for the first 1100 subjects): * healthy volunteers without genetically dependent disease and without such a disease in a family * healthy volunteer without the preliminary evidence of civilizational diseases such as hypertension, diabetes, autoimmune and tumor diseases or acute infectional diseases; clinically manifesting cardiovascular or pulmonary disability. * subject without permanent of long-term medication in the time of biological sampling. Exclusion Criteria: * not complying with inclusion criteria