NCT05715203 Aortic Stiffness in Patients With Genetic Aortopathies
| NCT ID | NCT05715203 |
| Status | Recruiting |
| Phase | — |
| Sponsor | IRCCS Policlinico S. Donato |
| Condition | Rare Diseases |
| Study Type | OBSERVATIONAL |
| Enrollment | 250 participants |
| Start Date | 2023-02-15 |
| Primary Completion | 2025-11-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 250 participants in total. It began in 2023-02-15 with a primary completion date of 2025-11-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this observational study is to study arterial stiffness in patients with thoracic ascending aortic aneurysms (TAA), either syndromic or non-syndromic. The main questions it aims to answer are: * Stratification of aortic risk based on arterial stiffness; Compare measurements with morphological and haemodynamic features of the ascending thoracic aorta. Participants will be asked to undergo non-invasive evaluation of blood pressure and arterial stiffness.
Eligibility Criteria
Inclusion Criteria: * Subjects with AAT, either syndromic or non syndromic; * Signed informed consent Exclusion Criteria: * Patients with early menopause and/or osteoporosis, rheumatic heart disease and active malignant tumours; * Patients with acute and chronic inflammatory conditions such as: chronic liver disease, chronic renal insufficiency and diseases affecting the thyroid system; * Seropositivity to HIV, HCV, HBsAg and SARS-CoV-2; * Pregnancy
Contact & Investigator
Alessandro Pini
PRINCIPAL INVESTIGATOR
Cardiovascular-Gentic Centre, IRCCS Policlinico San Donato
Frequently Asked Questions
Who can join the NCT05715203 clinical trial?
This trial is open to participants of all sexes, studying Rare Diseases. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05715203 currently recruiting?
Yes, NCT05715203 is actively recruiting participants. Contact the research team at alessandro.pini@grupposandonato.it for enrollment information.
Where is the NCT05715203 trial being conducted?
This trial is being conducted at San Donato Milanese, Italy.
Who is sponsoring the NCT05715203 clinical trial?
NCT05715203 is sponsored by IRCCS Policlinico S. Donato. The principal investigator is Alessandro Pini at Cardiovascular-Gentic Centre, IRCCS Policlinico San Donato. The trial plans to enroll 250 participants.
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