NCT05817929 Angiopoietin and Adverse Outcomes in Cardiac Surgery
| NCT ID | NCT05817929 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Centre Hospitalier Universitaire, Amiens |
| Condition | Cardiac Surgery |
| Study Type | INTERVENTIONAL |
| Enrollment | 200 participants |
| Start Date | 2023-03-23 |
| Primary Completion | 2026-04 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 200 participants in total. It began in 2023-03-23 with a primary completion date of 2026-04.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Cardiac surgery and cardiopulmonary bypass can lead to systemic organ failure trough excess inflammation and endothelial injury. The angiopoietin family represented by angiopoietin 1 and 2 can reflect endothelial injury by a decrease in angiopoietin 1 and an increase in angiopoietin 2. The investigators hypothesized that angiopoietin dysregulation could reflect organ failure related to cardiac surgery. The purpose of this project is to assess the association between angiopoietin dysregulation and adverse outcomes on cardiac surgery.
Eligibility Criteria
Inclusion Criteria: * adult patient scheduled for cardiac surgery under cardiopulmonary bypass Exclusion Criteria: * patient less than 18 years old, * redo surgery, * urgent surgery, * endocarditis, * aortic root repair surgery * aortic dissection * heart beating surgery, * heart transplantation
Contact & Investigator
Frequently Asked Questions
Who can join the NCT05817929 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Cardiac Surgery. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05817929 currently recruiting?
Yes, NCT05817929 is actively recruiting participants. Contact the research team at abouarab.osama@chu-amiens.fr for enrollment information.
Where is the NCT05817929 trial being conducted?
This trial is being conducted at Amiens, France.
Who is sponsoring the NCT05817929 clinical trial?
NCT05817929 is sponsored by Centre Hospitalier Universitaire, Amiens. The trial plans to enroll 200 participants.