NCT05197946 Anatomical and Functional Imaging Correlates of Chronic Pain in Cerebral Palsy
| NCT ID | NCT05197946 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Hugo W. Moser Research Institute at Kennedy Krieger, Inc. |
| Condition | Cerebral Palsy |
| Study Type | OBSERVATIONAL |
| Enrollment | 300 participants |
| Start Date | 2018-12-04 |
| Primary Completion | 2028-12 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 300 participants in total. It began in 2018-12-04 with a primary completion date of 2028-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The investigators hope to use MRI biomarkers to identify and characterize sensorimotor network disruption patterns associated with chronic pain and sensory deficits in CP. Investigators will use existing information in the medical record as well as subjective reports from interview, physical exam data, and anatomical and functional MRI data to non-invasively identify brain injury correlates of pain and sensory deficits.
Eligibility Criteria
Participants with CP (Survey-only): Inclusion Criteria: * Individual 8+ years of age * Diagnosis of cerebral palsy Exclusion Criteria: -None Neurotypical participants: (Survey-only): Inclusion Criteria: * Individual 8+ years of age * Adult subject able to indicate understanding and affirmative consent OR Adult/child subject unable to indicate understanding and affirmative consent AND subject assents AND LAR consents Exclusion Criteria: -Clinically-significant neurologic or developmental diagnosis Participants with CP (Survey and MRI): Inclusion Criteria: * Individual 8+ years of age * Adult subject able to indicate understanding and affirmative consent OR Adult subject unable to indicate understanding and affirmative consent AND subject assents AND LAR consents * Diagnosis of cerebral palsy * Clinical imaging demonstrating isolated periventricular white matter injury * Clinical judgment that all neurologic symptoms are attributable to non-progressive periventricular white matter injury * Able to lie still in scanner for 1.5 hours in at most 2 sessions and be able to have MRI Exclusion Criteria: -None Neurotypical participants (Survey and MRI): Inclusion Criteria: * Individual 8+ years of age * Adult subject able to indicate understanding and affirmative consent * Able to lie still in scanner for 1.5 hours and be able to have MRI Exclusion Criteria: -Clinically-significant neurologic or developmental diagnosis
Contact & Investigator
Eric Chin, MD
PRINCIPAL INVESTIGATOR
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Frequently Asked Questions
Who can join the NCT05197946 clinical trial?
This trial is open to participants of all sexes, aged 8 Years or older, studying Cerebral Palsy. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05197946 currently recruiting?
Yes, NCT05197946 is actively recruiting participants. Contact the research team at CPpainStudy@kennedykrieger.org for enrollment information.
Where is the NCT05197946 trial being conducted?
This trial is being conducted at Baltimore, United States, Baltimore, United States, Baltimore, United States, Baltimore, United States.
Who is sponsoring the NCT05197946 clinical trial?
NCT05197946 is sponsored by Hugo W. Moser Research Institute at Kennedy Krieger, Inc.. The principal investigator is Eric Chin, MD at Hugo W. Moser Research Institute at Kennedy Krieger, Inc.. The trial plans to enroll 300 participants.
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