NCT07416760 Analysis of the Composition of the Intestinal Microbiota in Patients Post-intestinal Anastomosis
| NCT ID | NCT07416760 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz |
| Condition | Abdominal Surgery |
| Study Type | OBSERVATIONAL |
| Enrollment | 30 participants |
| Start Date | 2026-02-14 |
| Primary Completion | 2026-02-14 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 30 participants in total. It began in 2026-02-14 with a primary completion date of 2026-02-14.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Recent research suggests a significant link between gut microbiota and anastomotic leakage (AL) in colorectal surgery. Patients who develop AL have a higher abundance of bacteria from the Lachnospiraceae family and lower microbial diversity. Considering the bibliographic data, our main interest is to analyze the microbial population of patients in our social environment and then look for differences in the microbiome between those who have suffered an anastomotic dehiscence (around 8-9% according to the results of our hospital's Surgery Department) and those who have not.
Eligibility Criteria
Inclusion Criteria: * Patients who have undergone colorectal intestinal anastomosis. * Signing of the informed consent form. * Age ≥18 years with good functional status. * Availability for postoperative follow-up. Exclusion Criteria: * Emergency surgery. * Intra-abdominal sepsis or previous dehiscence. * Severe immunosuppression. * Use of antibiotics in the 3 months prior to preoperative preparation. * Pregnancy or breastfeeding.
Contact & Investigator
Mariano García-Arranz, PhD
PRINCIPAL INVESTIGATOR
Health Research Institute Fundación Jiménez Díaz
Frequently Asked Questions
Who can join the NCT07416760 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Abdominal Surgery. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07416760 currently recruiting?
Yes, NCT07416760 is actively recruiting participants. Contact the research team at h.guadalajara@quironsalud.es for enrollment information.
Where is the NCT07416760 trial being conducted?
This trial is being conducted at Madrid, Spain.
Who is sponsoring the NCT07416760 clinical trial?
NCT07416760 is sponsored by Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz. The principal investigator is Mariano García-Arranz, PhD at Health Research Institute Fundación Jiménez Díaz. The trial plans to enroll 30 participants.