NCT06542991 An Open-label Study on the Clinical Efficacy of rTMS Intervention in PD
| NCT ID | NCT06542991 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Anhui Medical University |
| Condition | Transcranial Magnetic Stimulation |
| Study Type | INTERVENTIONAL |
| Enrollment | 20 participants |
| Start Date | 2024-09-01 |
| Primary Completion | 2024-12-31 |
Trial Parameters
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
Brief Summary
To demonstrate that intervention targeting the supplementary motor area (SMA) using precise navigation positioning can effectively improve motor symptoms in patients with Parkinson's disease.
Eligibility Criteria
Inclusion Criteria: 1. Age ≥40 years old 2. Meet Movement Disorder Society standards; 3. Have no history of drug adjustment within 4 weeks before and during treatment; 4. The MDS-UPDRS Ⅲ score ≥8, and the Hoehn-Yahr rating is 1-4 5. MMSE ≥24，able to cooperate with the completion of behavioral tests and transcranial magnetic stimulation therapy. Exclusion Criteria: 1. Head MRI/CT ruled out focal brain injury or severe leukoencephalopathy (Fazekas grade 3); 2. Various secondary parkinsonism syndromes (vascular parkinsonism, Parkinsonism combined with parkinsonism, drug parkinsonism, etc.); 3. Severe craniocerebral trauma, received craniocerebral surgery or deep brain stimulation treatment; 4. There are ferromagnetic implants in the body, such as cochlear implants, cardiac pacemakers, etc. 5. The person or first-degree relatives have a history of epilepsy, unexplained loss of consciousness, or are taking anticonvulsant drugs to treat epileptic seizures; 6. Diagnosed with a neuropsychiatri