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Recruiting NCT05065450

NCT05065450 Amygdala Memory Enhancement

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Clinical Trial Summary
NCT ID NCT05065450
Status Recruiting
Phase
Sponsor Washington University School of Medicine
Condition Brain Diseases
Study Type INTERVENTIONAL
Enrollment 90 participants
Start Date 2021-11-01
Primary Completion 2026-11-01

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 75 Years
Study Type INTERVENTIONAL
Interventions
Intracranial Stimulation

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 90 participants in total. It began in 2021-11-01 with a primary completion date of 2026-11-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The objective is to understand how amygdala activation affects other medial temporal lobe structures to prioritize long-term memories. The project is relevant to disorders of memory and to disorders involving affect and memory, including traumatic brain injury and post-traumatic stress disorder.

Eligibility Criteria

Inclusion Criteria: * Must be able to understand and speak English. * Able to provide informed consent. * Diagnosed with epilepsy. * Scheduled to undergo long-term intra-cranial video monitoring for seizure onset localization. * Must be implanted with intracranial depth electrodes to the left or right amygdala, hippocampus, and parahippocampal/perirhinal cortices. Exclusion Criteria: * Unable to understand and speak English. * Unable to provide informed consent. * Not diagnosed with epilepsy.

Contact & Investigator

Central Contact

Joan Atencio

✉ atencio@wustl.edu

📞 314-362-3114

Frequently Asked Questions

Who can join the NCT05065450 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 75 Years, studying Brain Diseases. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05065450 currently recruiting?

Yes, NCT05065450 is actively recruiting participants. Contact the research team at atencio@wustl.edu for enrollment information.

Where is the NCT05065450 trial being conducted?

This trial is being conducted at St Louis, United States.

Who is sponsoring the NCT05065450 clinical trial?

NCT05065450 is sponsored by Washington University School of Medicine. The trial plans to enroll 90 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology