NCT07018726 Addressing Emotional Distress in Dyads of Persons With a Young Onset Dementia (YOD) and Their Care-partners
| NCT ID | NCT07018726 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Massachusetts General Hospital |
| Condition | Young Onset Dementia |
| Study Type | INTERVENTIONAL |
| Enrollment | 388 participants |
| Start Date | 2026-01-28 |
| Primary Completion | 2030-07-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 388 participants in total. It began in 2026-01-28 with a primary completion date of 2030-07-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of the present investigation is to test the efficacy of a virtual, brief (6 sessions) dyadic (patient and care-partner together) intervention to prevent chronic emotional distress in dyads where one person is diagnosed with Young Onset Dementia (YOD). Through this study, we seek to address the unmet need of preventing chronic emotional distress in YOD dyads through a feasible, acceptable and credible program, and ideally enhance resiliency and improve wellbeing and quality of life in both members of the dyad.
Eligibility Criteria
Inclusion Criteria: * Between the ages of 18-65 at the time of enrollment \[both patient and care-partner\] * Diagnosis of young-onset dementia (FTD, PPA, AD, PCA, etc.) with symptom onset prior to age 65 \[patient\] * A designated care-partner willing and interested to participate \[both patient and care-partner\] * Received YOD diagnosis in the past 6 month \[patient\] * English fluency and literacy \[both patient and care-partner\] * Cognitive ability to understand study and research protocol in order to consent to study participation per referring neurologist \[both patient and care-partner\] * Patient and/or caregiver exhibit emotional distress on screening (using HADS D and/or HADS A scores \> 7) Exclusion Criteria: * An additional, terminal diagnosis such as cancer * Lack of access to internet and/or a device with a camera * Current untreated or unstable severe mental health conditions like bipolar disorder, schizophrenia, or active substance use
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07018726 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Young Onset Dementia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07018726 currently recruiting?
Yes, NCT07018726 is actively recruiting participants. Contact the research team at avranceanu@mgh.harvard.edu for enrollment information.
Where is the NCT07018726 trial being conducted?
This trial is being conducted at Boston, United States.
Who is sponsoring the NCT07018726 clinical trial?
NCT07018726 is sponsored by Massachusetts General Hospital. The trial plans to enroll 388 participants.