NCT07210203 Additional Effects of Neural Mobilization on Pain, Balance and Quality of Life in Diabetic Neuropathy
| NCT ID | NCT07210203 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Foundation University Islamabad |
| Condition | Diabetic Neuropathy |
| Study Type | INTERVENTIONAL |
| Enrollment | 32 participants |
| Start Date | 2024-09-13 |
| Primary Completion | 2025-12-10 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 32 participants in total. It began in 2024-09-13 with a primary completion date of 2025-12-10.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Diabetic Peripheral Neuropathy (DPN) is a common complication of diabetes, affecting up to 50% of patients and causing pain, numbness, and balance impairments, which increase the risk of falls, ulcers, and reduced quality of life. Current treatments mainly manage symptoms, highlighting the need for adjunctive approaches. This randomized controlled trial will evaluate the additional effects of Neural Mobilization (NM) on pain, balance, and quality of life in DPN. Thirty-two patients with type 2 diabetes and DPN will be recruited at Fauji Foundation Hospital and screened using the Michigan Neuropathy Screening Instrument (MNSI). Participants will be randomized into two groups: (1) NM plus Balance Training with standard care and (2) Balance Training alone, each for six weeks (two 30-minute sessions/week). Pain will be assessed using the Numeric Pain Rating Scale (NPRS), balance using the Berg Balance Scale, and quality of life using the Norfolk QOL-DN questionnaire. Outcome measures will be recorded at baseline and post-intervention. Ethical approval will be obtained from FUMC ERC, and data will be analyzed using SPSS v.22.
Eligibility Criteria
Inclusion Criteria: * Both genders. * Diagnosed cases of Diabetic Peripheral Neuropathy * Age 50-75 years. * Patients having history of type 2 Diabetes for at least 5 years. * Presence of neuropathic symptoms (pain, numbness, tingling, balance issues). * Patient having mild to moderate pain according to NPRS Exclusion Criteria: * Patients with Neurological Disorders like Stroke, multiple sclerosis, Parkinson's disease. * Chronic Pain Conditions or Conditions unrelated to DPN (e.g., fibromyalgia, osteoarthritis). * Foot Ulcers/Infection: Active ulcers or infections on lower limbs. * Uncontrolled Diabetes * Severe Balance Impairment Individuals unable to perform basic balance tests (e.g., unable to stand unaided for a few seconds).
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07210203 clinical trial?
This trial is open to participants of all sexes, aged 50 Years or older, up to 75 Years, studying Diabetic Neuropathy. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07210203 currently recruiting?
Yes, NCT07210203 is actively recruiting participants. Contact the research team at mariafareed@000gmail.com for enrollment information.
Where is the NCT07210203 trial being conducted?
This trial is being conducted at Islamabad, Pakistan.
Who is sponsoring the NCT07210203 clinical trial?
NCT07210203 is sponsored by Foundation University Islamabad. The trial plans to enroll 32 participants.