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Recruiting NCT06815887

Adding Magnesium Sulfate to Local Anesthetic in Combined Pectoral Nerve and Stellate Ganglion Block for Postoperative Pain Control After Modified Radical Mastectomy

Trial Parameters

Condition Magnesium Sulfate
Sponsor Cairo University
Study Type INTERVENTIONAL
Phase N/A
Enrollment 70
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2024-01-15
Completion 2025-07-31
Interventions
BupivacaineBupivacaine + Magnesium sulfate

Brief Summary

We aim to study the effect of adding magnesium sulfate as an adjuvant to the local anesthetic used in the combined Pectoralis Nerve Block II (PECS II) and stellate ganglion block for postoperative pain control in patients undergoing modified radical mastectomy.

Eligibility Criteria

Inclusion Criteria: * Age ≥18 years. * Female gender. * American Society of Anesthesiologists (ASA) physical status II or III. * Patients scheduled for elective modified radical mastectomy for breast cancer. * Body mass index (BMI): \> 20 kg/m2 and \< 40 kg/m2. Exclusion Criteria: * Bleeding tendency due to coagulopathy, * Patients with opioid dependence or alcohol or drug abuse, * Significant liver and renal sufficiency * Patients with psychiatric illnesses that prevent them from proper perception and assessment of pain. * Local infection at the site of the block. * Known hypersensitivity or allergy to magnesium sulfate or local anesthetics. * Patients with chronic pain syndromes or pre-existing neuropathic pain conditions. * Pregnant or lactating individuals.

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