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Recruiting NCT05246527

Acute Effects of Physical Exercise in Patients with Borderline Personality Disorder

Trial Parameters

Condition Borderline Personality Disorder
Sponsor University Hospital, Bonn
Study Type INTERVENTIONAL
Phase N/A
Enrollment 120
Sex ALL
Min Age 18 Years
Max Age 50 Years
Start Date 2022-02-08
Completion 2025-12-31
Interventions
Physical ExerciseControl Intervention

Brief Summary

The aim of the proposed project is to investigate the effects of a single session of physical exercise on stress regulation, cognitive and emotional functioning, and associated neurophysiological processes (saliva and blood samples) in patients with borderline personality disorder. A further aim is to identify the optimal exercise intensity (moderate vs. high intensity). The investigatiors expect that acute exercise will lead to positive effects on behavioral and biomarker level.

Eligibility Criteria

Inclusion Criteria: * estimated verbal intelligence quotient \>80 (MWT-B; Lehrl 2005) * patients: diagnosis of borderline personality disorder according to DSM-5 Exclusion Criteria: * neurological disorders * health conditions interfering with exercise safety, e.g. coronary heart disease * visual impairments that may interfere with performance of the cognitive tasks * endocrine disorders, e.g. hyperthyreosis or diabetes mellitus; * following psychiatric disorders: psychosis or affective disorders with psychotic symptoms, schizophrenia, substance abuse or dependence, autism spectrum disorders, anorexia nervosa; * healthy controls: BPD, intake of psychotropic drugs

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