NCT05246527 Acute Effects of Physical Exercise in Patients with Borderline Personality Disorder
| NCT ID | NCT05246527 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University Hospital, Bonn |
| Condition | Borderline Personality Disorder |
| Study Type | INTERVENTIONAL |
| Enrollment | 120 participants |
| Start Date | 2022-02-08 |
| Primary Completion | 2025-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 120 participants in total. It began in 2022-02-08 with a primary completion date of 2025-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The aim of the proposed project is to investigate the effects of a single session of physical exercise on stress regulation, cognitive and emotional functioning, and associated neurophysiological processes (saliva and blood samples) in patients with borderline personality disorder. A further aim is to identify the optimal exercise intensity (moderate vs. high intensity). The investigatiors expect that acute exercise will lead to positive effects on behavioral and biomarker level.
Eligibility Criteria
Inclusion Criteria: * estimated verbal intelligence quotient \>80 (MWT-B; Lehrl 2005) * patients: diagnosis of borderline personality disorder according to DSM-5 Exclusion Criteria: * neurological disorders * health conditions interfering with exercise safety, e.g. coronary heart disease * visual impairments that may interfere with performance of the cognitive tasks * endocrine disorders, e.g. hyperthyreosis or diabetes mellitus; * following psychiatric disorders: psychosis or affective disorders with psychotic symptoms, schizophrenia, substance abuse or dependence, autism spectrum disorders, anorexia nervosa; * healthy controls: BPD, intake of psychotropic drugs
Contact & Investigator
Frequently Asked Questions
Who can join the NCT05246527 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 50 Years, studying Borderline Personality Disorder. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05246527 currently recruiting?
Yes, NCT05246527 is actively recruiting participants. Contact the research team at aylin.mehren@ukbonn.de for enrollment information.
Where is the NCT05246527 trial being conducted?
This trial is being conducted at Bonn, Germany.
Who is sponsoring the NCT05246527 clinical trial?
NCT05246527 is sponsored by University Hospital, Bonn. The trial plans to enroll 120 participants.