NCT07123805 ACU_Knee: Role of Acupuncture in Knee Prosthetic Surgery
| NCT ID | NCT07123805 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Fondazione IRCCS Policlinico San Matteo di Pavia |
| Condition | Acupuncture Analgesia |
| Study Type | INTERVENTIONAL |
| Enrollment | 80 participants |
| Start Date | 2024-04-10 |
| Primary Completion | 2026-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 80 participants in total. It began in 2024-04-10 with a primary completion date of 2026-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Post-operative analgesia after total knee arthroplasty (TKA) has always been a challenge in the anesthesiological setting, having to combine good pain control and the need for early mobilization, both factors that can affect the quality of rehabilitation treatment, prosthetic functional outcome, the onset of chronic pain, joint stiffness and the consequent quality of life of the patient. Recent loco-regional anesthesia (LRA) techniques have made an essential contribution to peri-operative management in the fast-track perspective of surgery, in terms of optimization of analgesia and rapid functional recovery. Inadequate post-operative analgesia, by affecting the normal rehabilitation pathway, is associated with medium-long term complications, such as chronic pain, joint stiffness and patient dissatisfaction, which often compromise functional autonomy and quality of life of the patient and may require invasive treatments (surgical revision, unlocking under general anesthesia). The local and systemic inflammatory state, evidenced by peri-operative dosage of specific biomarkers, appears to be related to prosthetic outcome.
Eligibility Criteria
Inclusion Criteria: * Patients aged \> 18 years * Patients capable of providing informed consent * Unilateral total knee replacement surgery * Indication for surgery: primary osteoarthritis degeneration * Surgery performed electively Exclusion Criteria: * Patients aged \< 18 years * Patients incapable of providing informed consent * Patients with ASA class \> 3 * Pregnant women * Patients with rheumatoid arthritis or other autoimmune disorders * Patients with active infection under antibiotic treatment * Patients on chronic opioid therapy * Patients on chronic biological drug therapy * Patients with a history of corticosteroid use in the six months prior to surgery * Patients with a history of periarticular infiltration in the three months prior to surgery * Patients in whom loco-regional anesthesia is contraindicated * Patients in whom NSAID, cortisone, and paracetamol therapy is contraindicated * Bilateral total knee replacement surgery or prosthetic revision surgeries * Indication for surgery for causes other than primary osteoarthritis degeneration
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07123805 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Acupuncture Analgesia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07123805 currently recruiting?
Yes, NCT07123805 is actively recruiting participants. Contact the research team at d.passador@smatteo.pv.it for enrollment information.
Where is the NCT07123805 trial being conducted?
This trial is being conducted at Pavia, Italy.
Who is sponsoring the NCT07123805 clinical trial?
NCT07123805 is sponsored by Fondazione IRCCS Policlinico San Matteo di Pavia. The trial plans to enroll 80 participants.