| NCT ID | NCT07436351 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Thomas Jefferson University |
| Condition | Cystic Fibrosis (CF) |
| Study Type | INTERVENTIONAL |
| Enrollment | 60 participants |
| Start Date | 2026-01-20 |
| Primary Completion | 2027-04 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 60 participants in total. It began in 2026-01-20 with a primary completion date of 2027-04.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Acceptance and Commitment Therapy (ACT) tailored to meet the needs of adults living with cystic fibrosis (ACT with CF) is a newer form of talk therapy that has been shown to reduce anxiety \& depression and improve psychological flexibility, and value-based living. The investigators are now trying to find out whether a self-help version of this treatment (ACT with CF - Self Help Toolkit) is also effective in reducing anxiety and depression and improving psychological flexibility and value-based living in adults with CF. Adults with cystic fibrosis are at increased risk for anxiety and depression. This study examines whether a patient-facing therapy, ACT with CF - Self Help Toolkit can help to reduce anxiety and depression among adults with CF. This treatment can be accessed on the participant's smartphone.
Eligibility Criteria
Inclusion Criteria: * 18 years or older * Existing diagnosis of cystic fibrosis * PHQ-9 score \>4 or GAD-7 score \>4 Exclusion Criteria: * History of suicide attempts or acute suicidal ideation on clinical assessment * Presence of psychotic disorder or symptoms * Presence of psychiatric disorders that interfere with participation in the study, judged by the study or treating clinician * Presence of other medical conditions that interfere with participation in the study, judged by the study or treating clinician
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07436351 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Cystic Fibrosis (CF). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07436351 currently recruiting?
Yes, NCT07436351 is actively recruiting participants. Contact the research team at virginia.ohayer@jefferson.edu for enrollment information.
Where is the NCT07436351 trial being conducted?
This trial is being conducted at Philadelphia, United States.
Who is sponsoring the NCT07436351 clinical trial?
NCT07436351 is sponsored by Thomas Jefferson University. The trial plans to enroll 60 participants.