A Study of SH009 Injection in Patients With Advanced Solid Tumors.
Trial Parameters
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Brief Summary
Evaluate the efficacy and safety of SH009 injection therapy for patients with advanced solid tumors
Eligibility Criteria
Inclusion Criteria: * (1) Age≥18 years old at the time of informed consent, male or female; * (2) Subjects with histologically confirmed locally advanced, recurrent, or metastatic solid tumors (including but not limited to colorectal cancer, gastric cancer, hepatocellular carcinoma, head and neck cancer, breast cancer, non-small cell lung cancer, esophageal cancer, etc.) who have experienced disease progression or intolerance to at least one prior line of systemic therapy, and for whom no acceptable standard therapy exists or who cannot benefit from or tolerate standard therapy; * (3) Subjects must have at least one measurable lesion per RECIST 1.1 criteria. A lesion that has been previously irradiated can only be considered measurable if there is documented progression at that site following radiotherapy; * (4) Archival tumor tissue samples are available, or the subject agrees to undergo a tumor biopsy for the determination of PD-L1 and CD47 expression levels and other biomarker analy