NCT07137286 A Study of Genetic Influence on LDL Hyper-responsiveness in Patients Following a Ketogenic Diet
| NCT ID | NCT07137286 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Mayo Clinic |
| Condition | LDL Hyper-responsiveness |
| Study Type | OBSERVATIONAL |
| Enrollment | 100 participants |
| Start Date | 2025-09-11 |
| Primary Completion | 2027-08 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 100 participants in total. It began in 2025-09-11 with a primary completion date of 2027-08.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of this study is to identify whether individuals following a ketogenic diet who experience extreme LDL-C elevation, termed "hyper-responders", have identifiable genetic variations in genes involved in cholesterol absorption.
Eligibility Criteria
Inclusion Criteria: * 18 years of age or older * LDL-C \>170 mg/dL in response to starting a ketogenic diet Exclusion Criteria: * Patients who do not consent to blood draw for genetic testing * Those with LDL-C \<170 mg/dL on a ketogenic diet
Contact & Investigator
Stephen Kopecky, M.D.
PRINCIPAL INVESTIGATOR
Mayo Clinic
Frequently Asked Questions
Who can join the NCT07137286 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying LDL Hyper-responsiveness. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07137286 currently recruiting?
Yes, NCT07137286 is actively recruiting participants. Contact the research team at omar.saad@mayo.edu for enrollment information.
Where is the NCT07137286 trial being conducted?
This trial is being conducted at Rochester, United States.
Who is sponsoring the NCT07137286 clinical trial?
NCT07137286 is sponsored by Mayo Clinic. The principal investigator is Stephen Kopecky, M.D. at Mayo Clinic. The trial plans to enroll 100 participants.