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Recruiting Phase 4 NCT07223580

NCT07223580 A Study Of Corticosteroid On Postoperative Pain After Ureteroscopy For Urinary Calculi

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Clinical Trial Summary
NCT ID NCT07223580
Status Recruiting
Phase Phase 4
Sponsor Mayo Clinic
Condition Ureteroscopy
Study Type INTERVENTIONAL
Enrollment 90 participants
Start Date 2026-01-23
Primary Completion 2027-01-01

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
CorticosteroidPlacebo

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

Phase 4 studies follow an already-approved treatment in real-world conditions to monitor long-term safety and effectiveness.

This trial targets 90 participants in total. It began in 2026-01-23 with a primary completion date of 2027-01-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The purpose of this research is to evaluate if corticosteroid (prednisone) after ureteroscopy and placement of the stent will help alleviate postoperative pain control in addition to other normal postoperative pain medications

Eligibility Criteria

Inclusion Criteria: * Patients who are diagnosed with kidney or ureteral stones confirmed on imaging (CT of the abdomen or pelvis) and who elect for definitive treatment via ureteroscopy with placement of ureteral stent. * Age 18 years or older * Patients of either gender * Patients of all ethnic backgrounds * Cable of giving informed consent * Capable and willing to fulfill the requirements of the study. Exclusion Criteria: * History of chronic pain * Chronic use of opioids or other pain medication (\>12 weeks) * Known allergies to corticosteroids. * Known or suspected pregnancy * Inability to give informed consent or unable to meet requirements of the study for any reason. * Bilateral ureteroscopy * Current Corticosteroid Use * Diabetic patients who are insulin dependent

Contact & Investigator

Central Contact

Rev V. Vilasan Shylaja

📞 480-574-1466

Principal Investigator

Karen L. Stern, MD

PRINCIPAL INVESTIGATOR

Mayo Clinic

Frequently Asked Questions

Who can join the NCT07223580 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Ureteroscopy. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

What phase is the NCT07223580 trial and what does that mean for participants?

Phase 4 studies are conducted after a treatment has been approved. They monitor long-term safety and real-world effectiveness in a broader patient population.

Is NCT07223580 currently recruiting?

Yes, NCT07223580 is actively recruiting participants. Visit ClinicalTrials.gov or contact Mayo Clinic to inquire about joining.

Where is the NCT07223580 trial being conducted?

This trial is being conducted at Scottsdale, United States.

Who is sponsoring the NCT07223580 clinical trial?

NCT07223580 is sponsored by Mayo Clinic. The principal investigator is Karen L. Stern, MD at Mayo Clinic. The trial plans to enroll 90 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology