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post operative pain

Total Trials
4
Recruiting Now
4
Trial Phases
EARLY_Phase 1

Pain clinical trials span acute procedural pain, chronic musculoskeletal pain, neuropathic pain, and cancer-related pain β€” each requiring distinct trial designs and patient-reported outcome instruments. The regulatory demand for non-opioid alternatives has intensified the search for novel analgesic mechanisms, particularly ion channel targets and neurostimulation approaches.

Active trials evaluate Nav1.7/1.8 blockers, CGRP antagonists for new indications, spinal cord stimulation refinements, virtual reality-based pain management, and patient-specific ketamine infusion protocols. Pain trials increasingly use ecological momentary assessment (EMA) diary approaches over traditional recall-based pain rating scales.

Frequently Asked Questions — post operative pain Clinical Trials

How many clinical trials are currently recruiting for post operative pain?
ClinicalMetric currently tracks 4 actively recruiting clinical trials for post operative pain, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 4. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for post operative pain?
post operative pain research spans Phase 1 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a post operative pain clinical trial?
Eligibility criteria for post operative pain trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1
1
Top Sponsors
Kocaeli University 1 trial
Boston Children's Hospital 1 trial
Ain Shams University 1 trial
Texas Tech University Health Sciences Center 1 trial

Recruiting Clinical Trials

NCT06869967
Recruiting
Evaluation of Postoperative Pain Control in Ear Surgery
Enrollment
56 pts
Location
Turkey (Türkiye)
Sponsor
Kocaeli University
View Trial →
NCT06471348
Recruiting
Postoperative Pain Control in AIS Using Liposomal Bupivacaine vs. 0.25% Bupivacaine With Epinephrine
Enrollment
128 pts
Location
United States
Sponsor
Boston Children's Hospital
View Trial →
NCT06446830
Recruiting
The Analgesic Efficacy of Vitamin B Complex in Critically Ill Obstetrics After Caesarean Section
Enrollment
100 pts
Location
Egypt
Sponsor
Ain Shams University
View Trial →
NCT06349772 EARLY_Phase 1
Recruiting
Zynrelef vs Exparel: The Battle of Postoperative Pain Control After Robotic Sleeve Gastrectomy
Enrollment
130 pts
Location
United States
Sponsor
Texas Tech University Health S...
View Trial →

Related Conditions

analgesia (2) spinal fusion (1) cesarean section (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology