NCT06197685 A Novel Combinatory Approach to Maximize Functional Recovery of Learning and Memory in Multiple Sclerosis
| NCT ID | NCT06197685 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Kessler Foundation |
| Condition | Multiple Sclerosis |
| Study Type | INTERVENTIONAL |
| Enrollment | 78 participants |
| Start Date | 2024-02-12 |
| Primary Completion | 2026-06-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 78 participants in total. It began in 2024-02-12 with a primary completion date of 2026-06-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this novel study is to compare the effect of a combined cognitive rehabilitation and exercise approach on new learning and memory (NLM) in persons with multiple sclerosis (pwMS) and mobility disability.
Eligibility Criteria
Inclusion Criteria: * Be within the ages of 18 and 70 years of age * Speak English as their primary language * Confirmed MS diagnosis by a neurologist * Be relapse and steroid-free for at least 30 days * Mild-to-moderate self-reported mobility disability, based on the Patient Determined Disease Steps scale (PDDS) * Currently physically inactive, based on the Godin Leisure Time Exercise Questionnaire (GLTEQ) * Right handedness Exclusion Criteria: * History of neurological disorders besides MS or history of uncontrolled psychiatric disorders (ex: major depression) * Have contraindications to exercise, based on the Physical Activity Readiness Questionnaire (PAR-Q) * Currently use medications that may impact cognition (ex: steroids, benzodiazepines) * Currently pregnant * Contraindication for MRI (metal or electronic devices in the body that are not considered MRI safe) * Severe cognitive impairment as measured by the Modified Telephone Interview of Cognitive Status (TICS-M)
Contact & Investigator
Carly Wender, PhD
PRINCIPAL INVESTIGATOR
Kessler Foundation
Frequently Asked Questions
Who can join the NCT06197685 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 70 Years, studying Multiple Sclerosis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06197685 currently recruiting?
Yes, NCT06197685 is actively recruiting participants. Contact the research team at cwender@kesslerfoundation.org for enrollment information.
Where is the NCT06197685 trial being conducted?
This trial is being conducted at East Hanover, United States.
Who is sponsoring the NCT06197685 clinical trial?
NCT06197685 is sponsored by Kessler Foundation. The principal investigator is Carly Wender, PhD at Kessler Foundation. The trial plans to enroll 78 participants.
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