SPONSOR
Hoffmann-La Roche
Total Trials
15
Recruiting
15
Phases
Phase 1, Phase 3, Phase 1, Phase 2
Conditions studied: OverweightObesityNeovascular Age-related Macular DegenerationHuntington DiseaseMetastatic Breast CancerMultiple SclerosisRelapsing Remitting Multiple SclerosisLocally Advanced Breast CancerSolid TumoursNeuromyelitis Optica Spectrum Disorder
NCT06982131 Phase 1
Recruiting
A Study Investigating the Safety of RO7795081 and the Effect of RO7795081 on How the Body Processes Pitavastatin and Rosuvastatin in Otherwise Healthy Overweight or Obese Adult Participants
Overweight
NCT06847542 Phase 3
Recruiting
A Study of 36-Week Refill Exchanges of Port Delivery System (PDS) With Ranibizumab in nAMD
Neovascular Age-related Macular Degeneration
NCT06826612 Phase 1, Phase 2
Recruiting
A Randomized Study of SPK-10001 Gene Therapy in Participants With Huntington's Disease
Huntington Disease
NCT05894239 Phase 3
Recruiting
A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo in Participants With PIK3CA-Mutated HER2-Positive Locally Advanced or Metastatic Breast Cancer
Metastatic Breast Cancer
NCT06780150
Recruiting
A Study to Investigate Effects of Ocrelizumab Treatment on Neurofilament Light Chain (NfL) Levels and Participant Satisfaction in Participants With Multiple Sclerosis (MS)
Multiple Sclerosis
NCT05949580
Recruiting
Study to Evaluate the Usability and Value of Integrated Digital Solutions in Medical Care of Participants With Multiple Sclerosis
Relapsing Remitting Multiple Sclerosis
NCT07347600
Recruiting
A Study to Evaluate the Effectiveness and Safety of Inavolisib in Participants With Endocrine-resistant, PIK3CA-mutated, Hormone Receptor-positive, HER2-negative Locally Advanced or Metastatic Breast Cancer
Locally Advanced Breast Cancer
NCT04529122
Recruiting
A Worldwide Cancer Registry Enrolling Participants Profiled With a Next-Generation Sequencing Test
Solid Tumours
NCT05199688 Phase 3
Recruiting
A Study To Evaluate Pharmacokinetics, Efficacy, Safety, Tolerability, And Pharmacodynamics Of Satralizumab In Pediatric Patients With Aquaporin-4 Antibody Positive Neuromyelitis Optica Spectrum Disorder (NMOSD)
Neuromyelitis Optica Spectrum Disorder
NCT06819891 Phase 3
Recruiting
A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
Moderately to Severely Active Crohns Disease
NCT06961370 Phase 1
Recruiting
A Study to Investigate Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), and Immunogenicity of RO7669330 in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)
Geographic Atrophy
NCT06704672
Recruiting
Clinical Study to Evaluate the Impact of the Accu-Chek SmartGuide CGM Solution on the Mean Change in Time in Range Compared With Self-Monitoring of Blood Glucose in Participants With Type 1 and Type 2 Diabetes Mellitus
Type 1 Diabetes Mellitus
NCT04524871 Phase 1, Phase 2
Recruiting
A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Advanced Liver Cancers (Morpheus-Liver)
Advanced Liver Cancers
NCT05562947 Phase 3
Recruiting
A Study of the Efficacy, Safety, and Pharmacokinetics (PK) of the Port Delivery System With Ranibizumab (PDS) in Chinese Participants With Neovascular Age-related Macular Degeneration (nAMD)
Neovascular Age-related Macular Degeneration
NCT06680817
Recruiting
A Real-World Study to Gain Clinical Insights Into Faricimab (FaReal Study)
Neovascular Age-related Macular Degeneration