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hypertension Clinical Trials in United States

Active clinical trials for hypertension with research sites in United States. All data sourced live from ClinicalTrials.gov — updated daily.

Active Trials: 25 // Recruiting: 25 Phases: EARLY_Phase 1, Phase 4 // Updated: Daily
Total Trials
25
Recruiting Now
25
Country
🇺🇸 United States

Active Trials in United States (25)

NCT00932139
Recruiting

Effect of Electro-Acupuncture on Blood Pressure

Enrollment
160 pts
Country
🇺🇸 United States
University of California, Irvine
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NCT05955339
Recruiting

Comparing Healthcare Visit Recording and Open Notes to Improve Chronic iLlness Care Experience in Older Adults

Enrollment
1,022 pts
Country
🇺🇸 United States
Dartmouth-Hitchcock Medical Center
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NCT05330221
Recruiting

Project 2: ACHIEVE- HF

Enrollment
364 pts
Country
🇺🇸 United States
Henry Ford Health System
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NCT04911491
Recruiting

Inspiratory Muscle Strength Training in Chronic Kidney Disease

Enrollment
108 pts
Country
🇺🇸 United States
University of Colorado, Denver
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NCT06966258
Recruiting

Inspire HER: Inspiring the Heart and Emotions for Radical Health

Enrollment
90 pts
Country
🇺🇸 United States
University of Alabama at Birmingham
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NCT06402968
Recruiting

Clevidipine for the Antihypertensive Treatment of Acute Intracerebral Hemorrhage

Enrollment
1,018 pts
Country
🇺🇸 United States
Zeenat Qureshi Stroke Institute
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NCT04532489 EARLY_Phase 1
Recruiting

Positron Emission Tomography (PET) Imaging of Cholesterol Trafficking: Clinical Evaluation of [18F]FNP-59 in Normal Human Subjects (Group 1)

Enrollment
6 pts
Country
🇺🇸 United States
Benjamin Viglianti
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NCT05000996
Recruiting

Gut Microbiota in Metabolic Surgery

Enrollment
300 pts
Country
🇺🇸 United States
Vanderbilt University Medical Cente...
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NCT05856591
Recruiting

Delivering Food Resources & Kitchen Skills (FoRKS) to Adults With Food Insecurity and Hypertension

Enrollment
200 pts
Country
🇺🇸 United States
Indiana University
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NCT03042988
Recruiting

Overnight Trials With Heat Stress in Autonomic Failure Patients With Supine Hypertension

Enrollment
20 pts
Country
🇺🇸 United States
Vanderbilt University Medical Cente...
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NCT06375694
Recruiting

Probiotic Effect on Dietary Nitrate to Plasma Nitrite Production ( OPEDNPN )

Enrollment
20 pts
Country
🇺🇸 United States
Wake Forest University
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NCT04546126 EARLY_Phase 1
Recruiting

Positron Emission Tomography (PET) Imaging of Cholesterol Trafficking: Clinical Evaluation of [18F]FNP-59 in Normal Human Subjects (Groups 2, 3 & 4)

Enrollment
24 pts
Country
🇺🇸 United States
Benjamin Viglianti
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NCT06039176
Recruiting

Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future

Enrollment
150 pts
Country
🇺🇸 United States
International Consortium of Circula...
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NCT05499507
Recruiting

The Path to Optimal Black Maternal Heart Health: Comparing Two CVD Risk Reduction Interventions (Change of HEART)

Enrollment
432 pts
Country
🇺🇸 United States
Temple University
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NCT06876233
Recruiting

Mobile Cued Adherence Therapy (mCAT) for Blood Pressure Medication

Enrollment
600 pts
Country
🇺🇸 United States
Chad Stecher@asu.edu
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NCT06886087
Recruiting

Assessment of Risks of Perinephric Fat Thickness to Adverse Renal Outcomes Post Donor Nephrectomy

Enrollment
100 pts
Country
🇺🇸 United States
Mayo Clinic
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NCT07420907
Recruiting

Study of the Progression of Chronic Cardiovascular Conditions

Enrollment
5,000 pts
Country
🇺🇸 United States
Prolaio
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NCT05555095
Recruiting

Examining Digital Health Care Delivery Models Through Medicaid Collaborative

Enrollment
19,331 pts
Country
🇺🇸 United States
OSF Healthcare System
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NCT06504914
Recruiting

Preparing FIM-BCS - A Lifestyle Modification for African-American Breast Cancer Survivors

Enrollment
24 pts
Country
🇺🇸 United States
University of Illinois at Chicago
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NCT05106036
Recruiting

Preventing Cognitive Decline by Reducing BP Target Trial

Enrollment
4,000 pts
Country
🇺🇸 United States
University of Texas Southwestern Me...
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NCT06778239
Recruiting

Childhood-Onset Essential Hypertension Natural History Study

Enrollment
2,300 pts
Country
🇺🇸 United States
National Human Genome Research Inst...
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NCT06397456
Recruiting

Intensive Patient Referral and Education Program Prior to Renal Replacement Therapy

Enrollment
180 pts
Country
🇺🇸 United States
University of Chicago
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NCT06605807
Recruiting

Optimizing Prescribing Decisions for Hospitalized Older Adults With Chronic Conditions

Enrollment
150 pts
Country
🇺🇸 United States
University of Pittsburgh
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NCT05168605
Recruiting

Assessing the Efficacy of Targeted Home Visits in the Management of Chronic Conditions

Enrollment
100 pts
Country
🇺🇸 United States
University of Texas Southwestern Me...
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NCT05030545 Phase 4
Recruiting

Cardiovascular Manifestations of MR Activation in Primary Aldosteronism: Pilot Clinical Study

Enrollment
40 pts
Country
🇺🇸 United States
Brigham and Women's Hospital
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Frequently Asked Questions

How many hypertension clinical trials are active in United States?
There are currently 25 active clinical trials for hypertension with sites in United States, of which 25 are actively recruiting patients.
How can I join a hypertension clinical trial in United States?
To join a hypertension clinical trial in United States, select a recruiting trial below and check the eligibility criteria. Contact the trial's principal investigator or the listed site in United States directly. All trials listed here are sourced from ClinicalTrials.gov, the official U.S. registry of clinical studies.
What phases are hypertension trials in United States?
Active hypertension trials in United States span EARLY_Phase 1, Phase 4. Phase I trials test safety, Phase II test efficacy, and Phase III compare against standard treatments in larger patient populations.
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All United States Trials → Global hypertension Trials → All Countries → All Trials →
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology