To join a hypertension clinical trial in United States, select a recruiting trial below and check the eligibility criteria. Contact the trial's principal investigator or the listed site in United States directly. All trials listed here are sourced from ClinicalTrials.gov, the official U.S. registry of clinical studies.

What phases are hypertension trials in United States?

Active hypertension trials in United States span Phase 4, Phase 1, Phase 2, Phase 2, EARLY_Phase 1, Phase 3. Phase I trials test safety, Phase II test efficacy, and Phase III compare against standard treatments in larger patient populations.

Browse More

All United States Trials → Global hypertension Trials → All Countries → All Trials →

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: September 2026 · Data Methodology

Active Trials in United States (24)

BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT

Autonomic Regulation of Blood Pressure in Premature and Early Menopausal Women

Cardiovascular Manifestations of MR Activation in Primary Aldosteronism: Pilot Clinical Study

Targeting Endoplasmic Reticulum Stress in Human Hypertension

Optimizing Sustainable Cuff Access and Training Pathways for Self-Measured Blood Pressure Monitoring in Primary Care

Medication Adherence Program

A Cardiometabolic Health Program Linked With Clinical-Community Support and Mobile Health Telemonitoring to Reduce Health Disparities

Pharmacy-led Transitions of Care Intervention to Improve Medication Adherence

Remote Fetal Monitoring in High Risk Pregnancies

Sympathetic-vascular Dysfunction in Obesity and Insulin Resistance (Vitamin C Study)

A Study to Evaluate ALN-AGT01 RVR in Adult Patients With Mild to Moderate Hypertension Pretreated With Zilebesiran

Conical Forearm and Cylindrical Upper Arm Non-Invasive Blood Pressure (NIBP) Measurements in Pregnant Patients

Preventing Cognitive Decline by Reducing BP Target Trial

Clevidipine for the Antihypertensive Treatment of Acute Intracerebral Hemorrhage

E3 Hypertension - A Team-based, Multidisciplinary Model in Addressing Barriers to Hypertension Control

Inspire HER: Inspiring the Heart and Emotions for Radical Health

Sympathetic Transduction in Obesity-associated Hypertension (OB-HTN)

Groceries Plus Multi-Component Lifestyle Intervention for Adults With Hypertension and Type 2 Diabetes

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

Groceries for Residents of Southeastern USA to Stop Hypertension

Examining the Circadian Timing Effects of the Hypotensive Response to Exercise

Clinical and Molecular Characteristics of Primary Aldosteronism in Blacks

HOPE-BP 2.0: Evaluating the Optimal Duration of Postpartum Remote Blood Pressure Monitoring

A Pivotal Study to Evaluate the Effectiveness of Isometric Handgrip Therapy in Elevated Blood Pressure and Hypertensive Subjects

Frequently Asked Questions