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hypertension Clinical Trials in United States

Active clinical trials for hypertension with research sites in United States. All data sourced live from ClinicalTrials.gov — updated daily.

Active Trials: 25 // Recruiting: 25 Phases: Phase 2, EARLY_Phase 1 // Updated: Daily
Total Trials
25
Recruiting Now
25
Country
🇺🇸 United States

Active Trials in United States (25)

NCT06596265
Recruiting

Community Park-Based Programs for Health Promotion: The Fit2Lead Prospective Cohort Study

Enrollment
1,000 pts
Country
🇺🇸 United States
Duke University
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NCT04752293
Recruiting

Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE)

Enrollment
125 pts
Country
🇺🇸 United States
Wake Forest University Health Scien...
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NCT07413159
Recruiting

The "Check, Monitor, Control Hypertension" Study is a 24-month Randomized Trial in Houston Targeting African Americans Aged 55+. It Combines Pharmacist Counseling and CHW Support to Improve Blood Pressure Control in Hypertension Management.

Enrollment
480 pts
Country
🇺🇸 United States
Texas Southern University
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NCT06822439
Recruiting

Remote Fetal Monitoring in High Risk Pregnancies

Enrollment
50 pts
Country
🇺🇸 United States
Beth Israel Deaconess Medical Cente...
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NCT07238556
Recruiting

A Novel Digital Tool Clinicians Can Use to Prescribe Exercise to Patients With Cardiovascular Disease Risk Factors

Enrollment
72 pts
Country
🇺🇸 United States
University of Connecticut
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NCT06049420
Recruiting

Lifestyle Medicine: Establishing Clinical Approaches to Chronic Disease for Rural Patients

Enrollment
95 pts
Country
🇺🇸 United States
West Virginia School of Osteopathic...
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NCT07511361 Phase 2
Recruiting

Study of Efficacy and Safety of Tonlamarsen in Participants With a Recent Hospitalization and a Concurrent Episode of Acute Severe Hypertension

Enrollment
140 pts
Country
🇺🇸 United States
Kardigan, Inc.
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NCT05168605
Recruiting

Assessing the Efficacy of Targeted Home Visits in the Management of Chronic Conditions

Enrollment
100 pts
Country
🇺🇸 United States
University of Texas Southwestern Me...
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NCT06932029
Recruiting

SMBP Study: Improving High Blood Pressure in Older Adults With Multiple Chronic Diseases

Enrollment
930 pts
Country
🇺🇸 United States
Korey Kennelty
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NCT04838678 EARLY_Phase 1
Recruiting

Sympathetic Transduction in Obesity-associated Hypertension (OB-HTN)

Enrollment
100 pts
Country
🇺🇸 United States
University of Texas Southwestern Me...
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NCT02966665 Phase 1
Recruiting

: Vascular Function in Health and Disease

Enrollment
420 pts
Country
🇺🇸 United States
D. Walter Wray
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NCT07725250
Recruiting

Behavioral Interventions Combining AI/ML and Personalized Medicine to Reduce Cardiovascular Risk - Randomized Controlled Trial

Enrollment
3,000 pts
Country
🇺🇸 United States
National Bureau of Economic Researc...
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NCT06907524
Recruiting

Preventative Screening and Health Coaching in a Food Insecure Population

Enrollment
200 pts
Country
🇺🇸 United States
Rush University Medical Center
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NCT07194733
Recruiting

Supporting VETerans With Kidney Disease Through Food As Medicine

Enrollment
20 pts
Country
🇺🇸 United States
VA Eastern Colorado Health Care Sys...
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NCT03374215
Recruiting

Clinical and Molecular Characteristics of Primary Aldosteronism in Blacks

Enrollment
1,150 pts
Country
🇺🇸 United States
National Institute of Diabetes and ...
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NCT06062394
Recruiting

Penn Medicine Healthy Heart

Enrollment
1,980 pts
Country
🇺🇸 United States
University of Pennsylvania
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NCT05703386
Recruiting

Imaging the Pathogenesis of Cerebral Small Vessel Disease

Enrollment
50 pts
Country
🇺🇸 United States
Johns Hopkins University
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NCT06557005
Recruiting

Facilitated Transitions From Postpartum to Primary Care Coordination for People With Chronic Conditions

Enrollment
1,320 pts
Country
🇺🇸 United States
Massachusetts General Hospital
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NCT03042988
Recruiting

Overnight Trials With Heat Stress in Autonomic Failure Patients With Supine Hypertension

Enrollment
20 pts
Country
🇺🇸 United States
Vanderbilt University Medical Cente...
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NCT07693699
Recruiting

Optimizing Sustainable Cuff Access and Training Pathways for Self-Measured Blood Pressure Monitoring in Primary Care

Enrollment
150 pts
Country
🇺🇸 United States
Wake Forest University Health Scien...
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NCT06281665 Phase 4
Recruiting

Treatment With Aspirin After Preeclampsia: TAP Trial

Enrollment
60 pts
Country
🇺🇸 United States
Malamo Countouris
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NCT06132477 Phase 4
Recruiting

Impact GLP-1 Agonists Following Bariatric

Enrollment
150 pts
Country
🇺🇸 United States
University of Missouri-Columbia
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NCT06868719
Recruiting

Ketone Ester And Salt (KEAS) in Older Adults

Enrollment
35 pts
Country
🇺🇸 United States
Indiana University
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NCT06730230
Recruiting

Partners in Control, Phase II: Using Remote Monitoring Technology With Community Health Workers to Support Hypertension Management for Latinx Patients

Enrollment
300 pts
Country
🇺🇸 United States
NYU Langone Health
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NCT07758634 Phase 1, Phase 2
Recruiting

A Trial Evaluating Safety, Tolerability and Efficacy of CTX340 in Participants With Hypertension

Enrollment
69 pts
Country
🇺🇸 United States
CRISPR Therapeutics AG
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Frequently Asked Questions

How many hypertension clinical trials are active in United States?
There are currently 25 active clinical trials for hypertension with sites in United States, of which 25 are actively recruiting patients.
How can I join a hypertension clinical trial in United States?
To join a hypertension clinical trial in United States, select a recruiting trial below and check the eligibility criteria. Contact the trial's principal investigator or the listed site in United States directly. All trials listed here are sourced from ClinicalTrials.gov, the official U.S. registry of clinical studies.
What phases are hypertension trials in United States?
Active hypertension trials in United States span Phase 2, EARLY_Phase 1, Phase 1, Phase 4, Phase 1, Phase 2. Phase I trials test safety, Phase II test efficacy, and Phase III compare against standard treatments in larger patient populations.
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All United States Trials → Global hypertension Trials → All Countries → All Trials →
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: November 2026  ·  Data Methodology