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transcatheter aortic valve replacement

Total Trials
4
Recruiting Now
4
Trial Phases
Various

ClinicalMetric tracks all active clinical trials for transcatheter aortic valve replacement sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — transcatheter aortic valve replacement Clinical Trials

How many clinical trials are currently recruiting for transcatheter aortic valve replacement?
ClinicalMetric currently tracks 4 actively recruiting clinical trials for transcatheter aortic valve replacement, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 4. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for transcatheter aortic valve replacement?
transcatheter aortic valve replacement research spans multiple clinical trial phases. Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a transcatheter aortic valve replacement clinical trial?
Eligibility criteria for transcatheter aortic valve replacement trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Top Sponsors
Erasmus Medical Center 1 trial
Niguarda Hospital 1 trial
Insel Gruppe AG, University Hospital Bern 1 trial
Institut universitaire de cardiologie et de pneumologie de Québec, University Laval 1 trial

Recruiting Clinical Trials

NCT07872020
Recruiting
SYMmetric Valve fraME Expansion To Reduce hYpoattenuated Leaflet Thickening After Balloon-expandable TAVI: the SYMMETRY Trial
Enrollment
422 pts
Location
Germany, Netherlands
Sponsor
Erasmus Medical Center
View Trial →
NCT06000943
Recruiting
Ischemic And Bleeding Risk Assessment After TAVR
Enrollment
2,500 pts
Location
Belgium, Chile, Czec...
Sponsor
Niguarda Hospital
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NCT06559332
Recruiting
Coronary Artery Disease Assessment Strategies in TAVI Patients
Enrollment
546 pts
Location
Switzerland
Sponsor
Insel Gruppe AG, University Ho...
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NCT06420830
Recruiting
Valve Performance of the SAPIEN 3 Ultra RESILIA Valve: A Prospective Registry With Central Echocardiography Analysis.
Enrollment
150 pts
Location
Canada
Sponsor
Institut universitaire de card...
View Trial →

Related Conditions

aortic valve stenosis (2) aortic valve stenosis and or insufficiency (1) hypoattenuated leaflet thickening (1) valve expansion (1) coronary artery disease (1) heart disease risk factors (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: November 2026  ·  Data Methodology