Medical Condition

aortic valve stenosis

Total Trials

12

Recruiting Now

12

Trial Phases

Phase 2, Phase 4

ClinicalMetric tracks all active clinical trials for aortic valve stenosis sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — aortic valve stenosis Clinical Trials

How many clinical trials are currently recruiting for aortic valve stenosis?

ClinicalMetric currently tracks 12 actively recruiting clinical trials for aortic valve stenosis, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 12. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.

What trial phases are available for aortic valve stenosis?

aortic valve stenosis research spans Phase 2 (1 trial), Phase 4 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.

How do I find out if I qualify for a aortic valve stenosis clinical trial?

Eligibility criteria for aortic valve stenosis trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.

Trial Phases

Phase 2

Phase 4

Top Sponsors

McGill University Health Centre/Research Institute of the McGill University Health Centre 1 trial

Imperial College London 1 trial

Meril Life Sciences Pvt. Ltd. 1 trial

HemoCept Inc. 1 trial

Insel Gruppe AG, University Hospital Bern 1 trial

Recruiting Clinical Trials

NCT05930899

Recruiting

Translational-Omics in Aortic Stenosis (TOmAS) Biobank

McGill University Health Centr...

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NCT06602609

Recruiting

Remote Cardiovascular Monitoring in Post-TAVI Patients

Imperial College London

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NCT04275726

Recruiting

LANDMARK Trial: a Randomised Controlled Trial of Myval THV

Enrollment

988 pts

Location

Belarus, Brazil, Cro...

Sponsor

Meril Life Sciences Pvt. Ltd.

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NCT07205341

Recruiting

Detecting Changes in Arterial Blood Volume and Cardiac Efficiency

Structured Shared Decision Making for Patients Undergoing SAVR or TAVR

Insel Gruppe AG, University Ho...

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NCT05862558

Recruiting

Intravascular Lithotripsy in High Risk Calcified Iliac Anatomy for Transfemoral TAVR

Baylor Research Institute

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NCT04613193

Recruiting

Blood Pressure Reduction in Patients With Asymptomatic Aortic VALVE Stenosis

Impact of Local Tissue Inflammation on Intramyocardial Conduction Pathways Post Percutaneous Valve : Evaluation by Positron Emission Tomography on Exploratory Cohort

University Hospital, Brest

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NCT05788770

Recruiting

Preoperative CT-imaging with Patient-specific Computer Simulation in Transcatheter Aortic Valve Replacement

Angiotensin Receptor Blockers in Aortic Stenosis

Institut universitaire de card...

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NCT03549559

Recruiting

Imaging Histone Deacetylase in the Heart

Massachusetts General Hospital

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NCT07145463

Recruiting

Prospective, Multicenter, Randomized Controlled Clinical Study Evaluating the VitaFlow Liberty® Flex Transcatheter Aortic Valve Delivery System for the Treatment of Severe Aortic Stenosis Lesions

Shanghai Zhongshan Hospital

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Related Conditions

cardiovascular diseases (1) cardiac conduction disturbance (1) digital health (1) transcatheter aortic valve implantation (1) tavi (1) symptomatic aortic stenosis (1) iliac disease (1) hypertension essential (1) heart failure (1) aortic stenosis (1) heart failure with normal ejection fraction (1) left ventricular hypertrophy (1)

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: September 2026 · Data Methodology