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opioid withdrawal

Total Trials
4
Recruiting Now
4
Trial Phases
Phase 2, Phase 1, Phase 2

ClinicalMetric tracks all active clinical trials for opioid withdrawal sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — opioid withdrawal Clinical Trials

How many clinical trials are currently recruiting for opioid withdrawal?
ClinicalMetric currently tracks 4 actively recruiting clinical trials for opioid withdrawal, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 4. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for opioid withdrawal?
opioid withdrawal research spans Phase 1 (1 trial), Phase 2 (3 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a opioid withdrawal clinical trial?
Eligibility criteria for opioid withdrawal trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1
1
Phase 2
3
Top Sponsors
University of Maryland, Baltimore 2 trials
Payel Roy 1 trial
Medical University of South Carolina 1 trial

Recruiting Clinical Trials

NCT07079826
Recruiting

Sparrow Link Neuromodulation Device for Opioid Withdrawal Management in Hospitalized Adults With Opioid Use Disorder

Enrollment
50 pts
Location
United States
Sponsor
Payel Roy
View Trial →
NCT05027919 Phase 2
Recruiting

Assessing a Clinically-meaningful Opioid Withdrawal Phenotype

Enrollment
60 pts
Location
United States
Sponsor
University of Maryland, Baltim...
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NCT05511909 Phase 2
Recruiting

Evaluating Buspirone to Treat Opioid Withdrawal

Enrollment
100 pts
Location
United States
Sponsor
University of Maryland, Baltim...
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NCT06442566 Phase 1, Phase 2
Recruiting

ACTION: Trial of Adding Buprenorphine, CBT, and TMS to Improve Outcomes of Long-Term Opioid Therapy for Chronic Pain

Enrollment
240 pts
Location
United States
Sponsor
Medical University of South Ca...
View Trial →
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology