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high grade gliomas

Total Trials
5
Recruiting Now
5
Trial Phases
Phase 1, EARLY_Phase 1, Phase 1, Phase 2

ClinicalMetric tracks all active clinical trials for high grade gliomas sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — high grade gliomas Clinical Trials

How many clinical trials are currently recruiting for high grade gliomas?
ClinicalMetric currently tracks 5 actively recruiting clinical trials for high grade gliomas, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 5. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for high grade gliomas?
high grade gliomas research spans Phase 1 (4 trials), Phase 2 (2 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a high grade gliomas clinical trial?
Eligibility criteria for high grade gliomas trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1
4
Phase 2
2
Top Sponsors
Beijing Biotech 1 trial
Children's National Research Institute 1 trial
Eben Rosenthal 1 trial
Trogenix ltd 1 trial
M.D. Anderson Cancer Center 1 trial

Recruiting Clinical Trials

NCT07551336 Phase 1
Recruiting
Dual-Targeting CAR-NK Cells for Recurrent/Progressive Glioblastoma and High-Grade Glioma
Enrollment
36 pts
Location
China
Sponsor
Beijing Biotech
View Trial →
NCT07664176 Phase 1
Recruiting
NgFUS NIVO: NeuroNavigation-Guided Focused Ultrasound With Nivolumab in Relapsed and Progressive DMG and Other High Grade Brain Tumors
Enrollment
30 pts
Location
United States
Sponsor
Children's National Research I...
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NCT07210632 EARLY_Phase 1
Recruiting
Window Trial of Fluorescently Labeled Nivolumab-IRDye800 (Nivo800) in High Grade Glioma (HGG)
Enrollment
38 pts
Location
United States
Sponsor
Eben Rosenthal
View Trial →
NCT07346144 Phase 1, Phase 2
Recruiting
Study of an AAV Mediated Dual-Payload Gene Therapy in Patients With High Grade Glioma
Enrollment
68 pts
Location
United States, Unite...
Sponsor
Trogenix ltd
View Trial →
NCT07649070 Phase 2
Recruiting
Phase 2 Trial of G207 + 5 Gy Radiation for Children With High-Grade Gliomas
Enrollment
38 pts
Location
United States
Sponsor
M.D. Anderson Cancer Center
View Trial →

Related Conditions

recurrent glioblastoma (2) malignant glioma (1) glioblastoma (1) recurrent high grade gliomas (1) diffuse midline glioma or diffuse intrinsic pontine glioma (1) medulloblastoma recurrent (1) ependymoma recurrent (1) atypical teratoid rhabdoid tumor atrt of the cns (1) brain tumor recurrent (1) brain cancer (1) hgg (1) glioma (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: November 2026  ·  Data Methodology