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chronic post operative pain

Total Trials
3
Recruiting Now
3
Trial Phases
Various

Pain clinical trials span acute procedural pain, chronic musculoskeletal pain, neuropathic pain, and cancer-related pain β€” each requiring distinct trial designs and patient-reported outcome instruments. The regulatory demand for non-opioid alternatives has intensified the search for novel analgesic mechanisms, particularly ion channel targets and neurostimulation approaches.

Active trials evaluate Nav1.7/1.8 blockers, CGRP antagonists for new indications, spinal cord stimulation refinements, virtual reality-based pain management, and patient-specific ketamine infusion protocols. Pain trials increasingly use ecological momentary assessment (EMA) diary approaches over traditional recall-based pain rating scales.

Frequently Asked Questions — chronic post operative pain Clinical Trials

How many clinical trials are currently recruiting for chronic post operative pain?
ClinicalMetric currently tracks 3 actively recruiting clinical trials for chronic post operative pain, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 3. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for chronic post operative pain?
chronic post operative pain research spans multiple clinical trial phases. Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a chronic post operative pain clinical trial?
Eligibility criteria for chronic post operative pain trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Top Sponsors
Consorci Sanitari de l'Alt Penedès i Garraf 1 trial
Helen Koechlin 1 trial
Beijing Tiantan Hospital 1 trial

Recruiting Clinical Trials

NCT05920382
Recruiting

Radiofrequency Ablation for the Treatment of Post-knee Arthroplasty Chronic Pain.

Enrollment
86 pts
Location
Spain
Sponsor
Consorci Sanitari de l'Alt Pen...
View Trial →
NCT05816174
Recruiting

Longitudinal Study of Chronic Postsurgical Pain in Children and Adolescents

Enrollment
281 pts
Location
Switzerland
Sponsor
Helen Koechlin
View Trial →
NCT05795478
Recruiting

Effects of Oxycodone Combined With Pregabalin on Chronic Postsurgical Pain in Spinal Surgery

Enrollment
264 pts
Location
China
Sponsor
Beijing Tiantan Hospital
View Trial →
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology