| NCT ID | NCT07696741 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University Health Network, Toronto |
| Condition | Chronic Low Back Pain (CLBP) |
| Study Type | INTERVENTIONAL |
| Enrollment | 30 participants |
| Start Date | 2026-07-15 |
| Primary Completion | 2027-06 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 30 participants in total. It began in 2026-07-15 with a primary completion date of 2027-06.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this clinical trial is to learn whether Pain Reprocessing Therapy (PRT) is a feasible and acceptable treatment to complete for working-age adults (ages 18-65) with chronic low back pain. The main questions it aims to answer are: Is PRT acceptable and feasible for people with chronic low back pain to complete? Does PRT help reduce pain intensity and interference, while improving functional outcomes in people with chronic low back pain? Researchers will compare PRT to a Monitoring and Education Program to see whether participants who receive PRT experience greater improvements in pain, daily functioning, and well-being. Participants will: * Be randomly assigned to the PRT group or the Monitoring and Education group * Participate in 8 intervention sessions over an 8-week period * Wear an activity monitor for 8 weeks * Attend a follow-up assessment after completing the intervention and another assessment 3 months later Please note that ClinicalTrials.gov will be used solely as a public study registry and not as a participant recruitment tool. The study team will not recruit participants or accept self-referrals through ClinicalTrials.gov. All participant recruitment will occur only through the Research Ethics Board (REB) approved recruitment methods.
Eligibility Criteria
Inclusion Criteria: * Working age adults (18-65) * Male or Female at birth * Persisting back pain for at least 3 months occurring at least half of the days in the past 6 months * Pain score of at least 4/10 (on a 10-point rating scale) * Ability to speak and understand English in order to follow study procedures and engage in study interventions. Exclusion Criteria: * Compensation seeking claim/litigation/WSIB claim * Severe active psychiatric disorders (e.g., psychosis, substance use disorder) * An active medical issue such as untreated inflammatory disorder (e.g. ankylosing spondylitis, psoriatic arthritis) * Active cancers affecting the spine or body * Unexplained unintended weight loss of 20 lbs. or more in the past year * Inability to control bowel or bladder, function * Individuals who have received or are currently receiving one-on-one or group psychotherapy for chronic low back pain within the past 2 years (e.g., mindfulness, meditation, cognitive behavioural therapy, acceptance and commitment therapy, pain reprocessing therapy, or emotional awareness and exposure therapy). * Logistical or technical barriers (e.g. transportation challenges, scheduling constraints, or difficulty using fitness trackers
Contact & Investigator
Andrea D Furlan, MD PhD
PRINCIPAL INVESTIGATOR
University Health Network, Toronto
Frequently Asked Questions
Who can join the NCT07696741 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Chronic Low Back Pain (CLBP). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07696741 currently recruiting?
Yes, NCT07696741 is actively recruiting participants. Contact the research team at Pain@uhn.ca for enrollment information.
Where is the NCT07696741 trial being conducted?
This trial is being conducted at Toronto, Canada.
Who is sponsoring the NCT07696741 clinical trial?
NCT07696741 is sponsored by University Health Network, Toronto. The principal investigator is Andrea D Furlan, MD PhD at University Health Network, Toronto. The trial plans to enroll 30 participants.