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Recruiting NCT06823492

NCT06823492 Investigating the Impacts of Early Life Experience on the Brain & Behaviour

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Clinical Trial Summary
NCT ID NCT06823492
Status Recruiting
Phase
Sponsor University of Manchester
Condition Mental Health
Study Type OBSERVATIONAL
Enrollment 120 participants
Start Date 2023-04-01
Primary Completion 2025-12-30

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 25 Years
Study Type OBSERVATIONAL

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 120 participants in total. It began in 2023-04-01 with a primary completion date of 2025-12-30.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The aim of this study is to learn more about how early life experience influences the brain, behaviour, and the immune system later in life. This will help improve understanding of why certain early life experiences (e.g., adoption, stress and parental separation) can cause difficulties for some people when they are adults. The long-term goal of this research is to develop tools that could identify young people who are vulnerable to developing future problems, this will ensure people get the help that they need at the right time for them. This study will use psychological assessment, online games, brain imaging and blood sampling to help improve our understanding of how and why early life experience can influence mental health, cognition, brain development and the immune system later in life.

Eligibility Criteria

Inclusion Criteria: * Age 18-24 * Reside in Greater Manchester * You are not enrolled on a university degree course and do not hold a university degree qualification * Lived with one or both birth parents throughout childhood. * Able to travel to the University of Manchester * Able to understand the study information and participate in the assessment procedures described below (independently or with reading support from a researcher, friend or family member) * Able to read text on a computer screen (using glasses or contact lenses if required) * To sign up for this study one or more of the following statements should apply to you: 1. I am not currently in education employment or training, or I am unemployed. 2. I receive benefits from the Government e.g., housing benefits, universal credit, personal independent payment (PIP), disability benefit, job seekers allowance. 3. I am currently struggling due mental health problems or neurodiversity (e.g., depression, anxiety, ADHD, autism, eating disorder) Exclusion Criteria: * You were looked after by the local authority (e.g., foster, kinship care or residential children's home) or adopted during childhood. * Any experience of childhood trauma (including neglect, physical/verbal abuse, sexual abuse or exposure to domestic violence). * Your family required input from social services due to child protection concerns. * You are experiencing symptoms of and have been diagnosed with Post-Traumatic Stress Disorder (PTSD), borderline personality disorder (BPD), Emotionally Unstable Personality Disorder (EUPD).

Frequently Asked Questions

Who can join the NCT06823492 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 25 Years, studying Mental Health. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06823492 currently recruiting?

Yes, NCT06823492 is actively recruiting participants. Visit ClinicalTrials.gov or contact University of Manchester to inquire about joining.

Where is the NCT06823492 trial being conducted?

This trial is being conducted at Manchester, United Kingdom.

Who is sponsoring the NCT06823492 clinical trial?

NCT06823492 is sponsored by University of Manchester. The trial plans to enroll 120 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology