NCT07035847 Transaxillary TAVR With Solely Echocardiography Guidance
| NCT ID | NCT07035847 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Chinese Academy of Medical Sciences, Fuwai Hospital |
| Condition | Aortic Stenosis |
| Study Type | INTERVENTIONAL |
| Enrollment | 20 participants |
| Start Date | 2024-10-01 |
| Primary Completion | 2026-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 20 participants in total. It began in 2024-10-01 with a primary completion date of 2026-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study aims to evaluate the safety and feasibility of performing transaxillary transcatheter aortic valve replacement (TA TAVR) guided solely by echocardiography in patients with severe aortic stenosis (AS).
Eligibility Criteria
Inclusion Criteria: 1. symptomatic severe AS determined by echocardiography and Doppler that requiring aortic valve replacement, defined as: mean gradient ≥40 mmHg, peak aortic velocity ≥4 m/s, and aortic valve area (AVA) ≤1 cm2 (or an indexed AVA ≤0.6 cm2/m2) 2. suitable for Transaxillary TAVR Exclusion Criteria: 1. required hybrid procedures or concomitant interventions on other cardiac malformations 2. inoperable due to extremely high surgical risk or severe comorbidities 3. untreated clinically significant (\>70% obstruction) proximal vessel coronary vascular disease amenable to revascularization 4. previously undergone aortic valve replacement.
Contact & Investigator
Xiangbin Pan, MD
PRINCIPAL INVESTIGATOR
Chinese Academy of Medical Sciences, Fuwai Hospital
Frequently Asked Questions
Who can join the NCT07035847 clinical trial?
This trial is open to participants of all sexes, studying Aortic Stenosis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07035847 currently recruiting?
Yes, NCT07035847 is actively recruiting participants. Contact the research team at panxiangbin@fuwaihospital.org for enrollment information.
Where is the NCT07035847 trial being conducted?
This trial is being conducted at Beijing, China.
Who is sponsoring the NCT07035847 clinical trial?
NCT07035847 is sponsored by Chinese Academy of Medical Sciences, Fuwai Hospital. The principal investigator is Xiangbin Pan, MD at Chinese Academy of Medical Sciences, Fuwai Hospital. The trial plans to enroll 20 participants.