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Recruiting NCT02602769
Whole Transcriptome Profiling and Metabolic Phenotyping in Children With ROHHAD Syndrome
Trial Parameters
Condition Childhood Obesity
Sponsor Columbia University
Study Type OBSERVATIONAL
Phase N/A
Enrollment 12
Sex ALL
Min Age 2 Years
Max Age 20 Years
Start Date 2015-11
Completion 2026-12
All Conditions
Interventions
Transcriptome profiling
Brief Summary
Rapid onset Obesity, Hypoventilation, Hypothalamic dysfunction and Autonomic Dysregulation (ROHHAD) is a syndrome named in 2007. The hallmark of the syndrome is the rapid onset obesity and dysregulation of central ventilation. There is little information about the metabolic changes that lead to the rapid onset obesity in these children. The investigators would like to study the metabolic phenotype of these children to understand the disturbances in energy balance that lead to the rapid onset obesity.
Eligibility Criteria
Inclusion Criteria: * Children with ROHHAD syndrome Exclusion Criteria: * Children with known genetic causes of obesity