NCT07621120 Wearable Accelerometers for Predicting Perioperative Risk in Elderly Patients
| NCT ID | NCT07621120 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Peking Union Medical College Hospital |
| Condition | Post Induction Hypotension |
| Study Type | OBSERVATIONAL |
| Enrollment | 100 participants |
| Start Date | 2026-06-15 |
| Primary Completion | 2027-09-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 100 participants in total. It began in 2026-06-15 with a primary completion date of 2027-09-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This single-center prospective cohort study is designed to evaluate whether preoperative physical activity measured by a wearable accelerometer is associated with cardiovascular autonomic function and whether it can help predict post-induction hypotension in elderly patients undergoing elective non-cardiac surgery. Patients aged 65 years or older scheduled for general anesthesia with tracheal intubation will undergo preoperative physical activity monitoring using an ActiGraph wearable accelerometer. Activity-related parameters, including sedentary time, light-, moderate-, and vigorous-intensity activity, daily step count, and sleep duration, will be recorded. Cardiovascular autonomic function will be assessed perioperatively using noninvasive continuous hemodynamic monitoring, with baroreflex sensitivity-related indices derived from continuous blood pressure and beat-to-beat timing data. The primary outcome is post-induction hypotension. Secondary outcomes include early intraoperative hypotension, postoperative complications, and 30-day mortality. This study aims to clarify the relationship between habitual physical activity and autonomic regulation in older surgical patients and to provide evidence supporting future prehabilitation strategies.
Eligibility Criteria
Inclusion Criteria: * Age ≥65 years * Scheduled for elective non-cardiac surgery * American Society of Anesthesiologists (ASA) physical status I-III * Planned to undergo general anesthesia * Planned tracheal intubation * The patient and family members are able to understand the study protocol, are willing to participate, and provide written informed consent Exclusion Criteria: * Severe vascular disease * Secondary hypertension * Limb tremor disorders, such as Parkinson disease * Inability to wear a wrist-based wearable accelerometer for any reason * Inability to measure upper-extremity blood pressure * Atrial fibrillation or other arrhythmias unsuitable for baroreflex sensitivity measurement * Mental or psychiatric conditions resulting in inability to cooperate with study procedures
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07621120 clinical trial?
This trial is open to participants of all sexes, aged 65 Years or older, studying Post Induction Hypotension. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07621120 currently recruiting?
Yes, NCT07621120 is actively recruiting participants. Contact the research team at Cuiqx_garfield@126.com for enrollment information.
Where is the NCT07621120 trial being conducted?
This trial is being conducted at Beijing, China.
Who is sponsoring the NCT07621120 clinical trial?
NCT07621120 is sponsored by Peking Union Medical College Hospital. The trial plans to enroll 100 participants.