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Recruiting NCT06447220

Washed Microbiota Transplantation for Malnutrition

Trial Parameters

Condition Malnutrition
Sponsor The Second Hospital of Nanjing Medical University
Study Type OBSERVATIONAL
Phase N/A
Enrollment 100
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2023-12-17
Completion 2030-12
Interventions
washed microbiota transplantation

Brief Summary

Malnutrition is a pathological condition in which dietary intake fails to meet the body's energetic or nutritional needs. It may be caused by macronutrient or micronutrient deficiencies, high energy expenditure, impaired nutrient absorption or assimilation. Malnutrition can affect all stages of life. In adults, malnutrition is strongly associated with poor clinical outcomes such as increased morbidity, increased mortality and prolonged hospitalization. In children, malnutrition can lead to growth retardation, cognitive impairment and immune dysfunction.

Eligibility Criteria

Inclusion Criteria: 1. Age ≥18 years old; 2. Meet any of the following two conditions: ①weight loss (\>5% weight loss in the past 6 months or \>10% weight loss in more than 6 months); ②low BMI (\<70 years old and BMI\<18.5kg/m2 or ≥70 years old and BMI\<22kg/m2); 3. Underwent washed microbiota transplantation. Exclusion Criteria: 1. Expected survival time \<3 months; 2. Women who are pregnant or breastfeeding; 3. Other patients deemed not suitable for enrollment by the investigator.

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