NCT06445933 Vitamin B6 and Depression in Pregnant and Peri-partum Women
| NCT ID | NCT06445933 |
| Status | Recruiting |
| Phase | — |
| Sponsor | National Taiwan University Hospital |
| Condition | Postpartum Depression |
| Study Type | INTERVENTIONAL |
| Enrollment | 150 participants |
| Start Date | 2024-07-05 |
| Primary Completion | 2026-09-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 150 participants in total. It began in 2024-07-05 with a primary completion date of 2026-09-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Perinatal depression is a highly prevalent and serious health issue during pregnancy. According to statistics, approximately one out of every ten postpartum women experiences this condition. Symptoms can manifest as mood fluctuations or emotional lows. Unfortunately, these symptoms are often overlooked by patients themselves or misinterpreted by others as normal adjustments to the new role of motherhood. Consequently, timely assistance and support are frequently lacking. To address this, the investigators urgently need effective preventive measures for perinatal depression before it escalates. Recent research suggests that simple oral supplementation of vitamin B6 may help prevent and alleviate perinatal depression to some extent. Vitamin B6 plays several crucial roles in the body, including regulating neurotransmission and mental health. Therefore, it could contribute to maintaining emotional stability and psychological balance. In contemporary times, numerous screening methods for perinatal depression involve questionnaires. However, these methods presuppose an awareness of the possibility of perinatal depression. Individuals who are unaware of these questionnaires may go undetected. Hence, our aim is to investigate whether cardiac electrophysiology results obtained through a wearable device could offer a more objective evaluation of the status of perinatal depression. Our plan involves conducting a prospective study to delve deeper into the preventive and therapeutic effects of vitamin B6 on perinatal depression in pregnant women. Through systematic experiments and data analysis, the investigators aim to explore the impact of vitamin B6 dosage, duration, and timing of administration. Ultimately, the investigators hope to provide evidence-based recommendations and guidance for clinical practice. The investigators' goal is to offer new insights and methods to protect the mental health of expectant mothers, ensuring a pleasant and healthy pregnancy journey for each one.
Eligibility Criteria
Inclusion Criteria: * Pregnant women at 24-28 weeks of gestation * Without a personal history of depression, bipolar disorder, schizophrenia, or other mental health conditions. Exclusion Criteria: * Allergic to Vitamin B6
Contact & Investigator
HanYing Chen
PRINCIPAL INVESTIGATOR
Attending physician
Frequently Asked Questions
Who can join the NCT06445933 clinical trial?
This trial is open to female participants only, aged 20 Years or older, up to 50 Years, studying Postpartum Depression. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06445933 currently recruiting?
Yes, NCT06445933 is actively recruiting participants. Contact the research team at hanyingchan@Hotmail.com for enrollment information.
Where is the NCT06445933 trial being conducted?
This trial is being conducted at Taipei, Taiwan.
Who is sponsoring the NCT06445933 clinical trial?
NCT06445933 is sponsored by National Taiwan University Hospital. The principal investigator is HanYing Chen at Attending physician. The trial plans to enroll 150 participants.
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