NCT07497711 Virtual Menstrual Pain Approaches in Females
| NCT ID | NCT07497711 |
| Status | Recruiting |
| Phase | Phase 2, Phase 3 |
| Sponsor | Nanyang Technological University |
| Condition | Pain (Visceral, Somatic, or Neuropathic) |
| Study Type | INTERVENTIONAL |
| Enrollment | 145 participants |
| Start Date | 2026-04-15 |
| Primary Completion | 2028-12-20 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
In Phase 2, researchers evaluate early signs of effectiveness. You may be randomized to receive the active treatment or a comparator. Monitoring continues closely.
This trial targets 145 participants in total. It began in 2026-04-15 with a primary completion date of 2028-12-20.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This research study is testing two self-care approaches that may help prevent or reduce period pain in young females with recurrent painful menstrual cramps. Participants will be placed by chance into 1 of 3 groups: auricular acupressure, Baduanjin qigong, or a self-care education comparison group. The auricular acupressure and Baduanjin groups will receive online training and then practice the treatment on their own for 12 weeks. The main question is whether these two approaches can reduce the severity of menstrual pain. The study will also look at whether they can improve other symptoms that often happen with period pain, such as tiredness, poor sleep, anxiety, low mood, trouble concentrating, and reduced physical function. Researchers will also study stool and blood-related biological markers to better understand whether changes in gut bacteria and body metabolism may be linked to symptom improvement. A total of 145 participants will take part in the study at NTU, and any side effects or other safety concerns will be checked every week.
Eligibility Criteria
Inclusion Criteria: * 16 - 35 years of age * Regular menstrual cycles (28 days ± 7 days) in 3 months prior to enrollment * Two or more episodes of menstrual cramps in the past 2 months, scored at least 4 points on the worst pain item of the Brief Pain Inventory (BPI) * Stated willingness to comply with all study procedures and availability for the duration of the study * Ability to download, install, and navigate the study-specific digital content and use its core functions for training, self-guided intervention administration, and data entry * Ability to understand the nature of the study and willingness to give informed consent. Exclusion Criteria: * Uncontrolled neurological diseases, immunodeficiency, bleeding disorders, and allergies * The presence of another Axis I disorder not in remission * Lactating or pregnant, or those planning to become pregnant in the coming half year * Undergoing other trials for pain management during the study period * Plan to initiate other pain therapies for menstrual pain management in the proceeding 3 months
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07497711 clinical trial?
This trial is open to female participants only, aged 16 Years or older, up to 35 Years, studying Pain (Visceral, Somatic, or Neuropathic). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
What phase is the NCT07497711 trial and what does that mean for participants?
Phase 2 trials evaluate whether the treatment shows signs of effectiveness while continuing to monitor safety. More participants are enrolled than in Phase 1 to help refine the treatment protocol.
Is NCT07497711 currently recruiting?
Yes, NCT07497711 is actively recruiting participants. Contact the research team at mingxiao.yang@ntu.edu.sg for enrollment information.
Where is the NCT07497711 trial being conducted?
This trial is being conducted at Singapore, Singapore.
Who is sponsoring the NCT07497711 clinical trial?
NCT07497711 is sponsored by Nanyang Technological University. The trial plans to enroll 145 participants.