NCT07426016 Video vs. Direct Laryngoscopy for Less Invasive Surfactant Administration
| NCT ID | NCT07426016 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Texas Southwestern Medical Center |
| Condition | Respiratory Distress Syndrome (Neonatal) |
| Study Type | INTERVENTIONAL |
| Enrollment | 100 participants |
| Start Date | 2026-06-11 |
| Primary Completion | 2028-06 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 100 participants in total. It began in 2026-06-11 with a primary completion date of 2028-06.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Many preterm babies born between 22-28+6 weeks' estimated gestational age (EGA) need surfactant, a medicine that helps the lungs. The goal of the study is to compare the use of video-based visualization to direct visualization during a procedure called less invasive surfactant administration (LISA). The main questions the study aims to answer are: 1) does one method of visualization have a increased rate of giving the medicine successfully on the first attempt? 2) what benefits are there of each method?
Eligibility Criteria
Inclusion Criteria: * Infants born ≤28 weeks GA successfully resuscitated in the delivery room (DR) and maintained on CPAP • Need for surfactant in the first 36 hours of life based on clinical assessment and/or meeting threshold per unit protocol Exclusion Criteria: * Infants born ≥29 weeks GA or * Infants with known congenital anomalies or * Infants who are determined by the primary care team to receive comfort care only or * Infants who are intubated at any time prior to surfactant administration
Contact & Investigator
Chokshi, MD
PRINCIPAL INVESTIGATOR
UT Southwestern
Frequently Asked Questions
Who can join the NCT07426016 clinical trial?
This trial is open to participants of all sexes, aged 0 Hours or older, up to 3 Days, studying Respiratory Distress Syndrome (Neonatal). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07426016 currently recruiting?
Yes, NCT07426016 is actively recruiting participants. Contact the research team at riti.chokshi@utsouthwestern.edu for enrollment information.
Where is the NCT07426016 trial being conducted?
This trial is being conducted at Dallas, United States.
Who is sponsoring the NCT07426016 clinical trial?
NCT07426016 is sponsored by University of Texas Southwestern Medical Center. The principal investigator is Chokshi, MD at UT Southwestern. The trial plans to enroll 100 participants.