NCT05729607 Vertical Soft Tissue Augmentation With CTG vs ADM
| NCT ID | NCT05729607 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Harvard Medical School (HMS and HSDM) |
| Condition | Implant Complication |
| Study Type | INTERVENTIONAL |
| Enrollment | 28 participants |
| Start Date | 2023-05-26 |
| Primary Completion | 2027-02-27 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 28 participants in total. It began in 2023-05-26 with a primary completion date of 2027-02-27.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The study aims at comparing two different approaches for vertical soft tissue augmentation at implant sites exhibiting soft tissue dehiscences: autogenous connective tissue graft vs acellular dermal matrix + enamel matrix derivative
Eligibility Criteria
Inclusion criteria: * Age ≥ 18 years * Periodontally and systemically healthy * Full-mouth plaque score and full-mouth bleeding score ≤ 20% (measured at four sites per tooth) * Presence of single functional dental implant in the anterior with a PSTD * Implants diagnosed as healthy (Berglundh et al., 2018) Exclusion criteria are: * Contraindications for surgery * Systemic condition (e.g. diabetes mellitus, HIV, cancer, etc) that could compromise wound healing * Patients pregnant or attempting to get pregnant (self-reported) * Untreated periodontitis * Untreated peri-implant mucositis or peri-implantitis (Berglundh et al., 2018) * Smoking, defined as self-reported daily habit. Occasional smokers won't be excluded * History of soft tissue grafting at the implant site within the last 6 months
Contact & Investigator
Lorenzo Tavelli, DDS, MS
PRINCIPAL INVESTIGATOR
Harvard School of Dental Medicine, Boston, USA
Frequently Asked Questions
Who can join the NCT05729607 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 99 Years, studying Implant Complication. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05729607 currently recruiting?
Yes, NCT05729607 is actively recruiting participants. Contact the research team at lorenzo_tavelli@hsdm.harvard.edu for enrollment information.
Where is the NCT05729607 trial being conducted?
This trial is being conducted at Boston, United States.
Who is sponsoring the NCT05729607 clinical trial?
NCT05729607 is sponsored by Harvard Medical School (HMS and HSDM). The principal investigator is Lorenzo Tavelli, DDS, MS at Harvard School of Dental Medicine, Boston, USA. The trial plans to enroll 28 participants.