NCT06554327 Ventilator Associated Pneumonia Multiplex PCR for Anti-Infective Regimens
| NCT ID | NCT06554327 |
| Status | Recruiting |
| Phase | — |
| Sponsor | CHU de Reims |
| Condition | Ventilator Associated Pneumonia |
| Study Type | INTERVENTIONAL |
| Enrollment | 265 participants |
| Start Date | 2025-03-06 |
| Primary Completion | 2026-09-06 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 265 participants in total. It began in 2025-03-06 with a primary completion date of 2026-09-06.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Ventilator-associated pneumonia (VAP) remains one of the main nosocomial infections acquired in the intensive care unit (ICU). VAP is pneumonia occurring 48 hours after intubation. Today, bronchoalveolar lavage (BAL) is used for microbiological diagnosis, with bacterial culture and antibiotic susceptibility results within 48 to 72 hours. Multiplex PCR can detect DNA of a number of bacteriae, as well as the presence of resistance genes. However, its clinical value in the ICU remains to be demonstrated. We think that the use of multiplex PCR with a panel adapted to the microbiology of VAP, could be an interesting method for clinicians in ICU.
Eligibility Criteria
inclusion criteria : * Adult patients, hospitalized in intensive care unit * on mechanical ventilation for at least 48 hours * Suspected VAP * With an indication for bronchoalveolar lavage (BAL) exclusion criteria : * Patients under legal protection or without social security coverage * Pregnant women * Previous episode of VAP during the same hospitalization
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06554327 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Ventilator Associated Pneumonia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06554327 currently recruiting?
Yes, NCT06554327 is actively recruiting participants. Contact the research team at agoury@chu-reims.fr for enrollment information.
Where is the NCT06554327 trial being conducted?
This trial is being conducted at Reims, France.
Who is sponsoring the NCT06554327 clinical trial?
NCT06554327 is sponsored by CHU de Reims. The trial plans to enroll 265 participants.