NCT07370727 Velocity-Based Resistance Training in Kidney Transplant Recipients
| NCT ID | NCT07370727 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Fundación Universitaria del Area Andina |
| Condition | Kidney Transplant Recipients |
| Study Type | INTERVENTIONAL |
| Enrollment | 12 participants |
| Start Date | 2025-10-29 |
| Primary Completion | 2026-06-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 12 participants in total. It began in 2025-10-29 with a primary completion date of 2026-06-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This randomized controlled trial aims to evaluate the effects of velocity-based resistance training on renal function and metabolic health in kidney transplant recipients. Participants will be randomized into two groups performing resistance training at different execution velocities (maximal intended vs. submaximal controlled). The intervention will last 12 weeks and include multi-joint exercises (squat, bench press, military press). Primary outcomes include renal function (serum creatinine, eGFR, blood urea nitrogen, uric acid) and metabolic markers (HDL, triglycerides, glucose, waist circumference, blood pressure). Secondary outcomes include muscle strength, force-velocity profile, anthropometry, physical activity, fitness perception, and adherence to immunosuppressive medication.
Eligibility Criteria
Inclusion Criteria: * Men and women aged 18 to 50 years. * Kidney transplant performed ≥12 months before enrollment. * Stable graft function in the previous 6 months (serum creatinine \< 1.5 mg/dL, no rejection episodes). * Written medical clearance from a nephrologist to perform moderate-to-vigorous physical activity. * Signed informed consent. Exclusion Criteria: * Active autoimmune disorders. * Recent coronary disease (≤6 months). * Severe musculoskeletal limitations incompatible with resistance training. * Diagnosis of diabetes mellitus (pre- or post-transplant). * Current active infection. * Use of immunosuppressive drugs with contraindications for exercise (e.g., mTOR inhibitors at baseline).
Frequently Asked Questions
Who can join the NCT07370727 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 50 Years, studying Kidney Transplant Recipients. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07370727 currently recruiting?
Yes, NCT07370727 is actively recruiting participants. Visit ClinicalTrials.gov or contact Fundación Universitaria del Area Andina to inquire about joining.
Where is the NCT07370727 trial being conducted?
This trial is being conducted at Bogotá, Colombia.
Who is sponsoring the NCT07370727 clinical trial?
NCT07370727 is sponsored by Fundación Universitaria del Area Andina. The trial plans to enroll 12 participants.
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