| NCT ID | NCT07134426 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Minnesota |
| Condition | Former Smoker |
| Study Type | INTERVENTIONAL |
| Enrollment | 100 participants |
| Start Date | 2026-09-01 |
| Primary Completion | 2027-09-01 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 100 participants in total. It began in 2026-09-01 with a primary completion date of 2027-09-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Some people who used to smoke cigarettes continue to be at higher risk of developing lung cancer, even years after quitting. This study will look to see if a specific chemical, phenanthrene, is broken down in the lungs of former smokers through more harmful pathways than never-smokers. If former smokers break down chemicals that enter their lungs through more harmful pathways this might be putting them at higher risk for developing lung cancer even though they quit smoking. This information may help find better ways to prevent or treat cancer in the future. This study is under an IND, but the drug is not being studied; instead, it is being used as a marker for drug metabolism.
Eligibility Criteria
Inclusion Criteria: * \> 21 years of age * In good physical \& mental health * In stable physical \& mental health * Have tried vaping * Former daily cigarette smokers who quit 1-20 year ago * Non-smokers who have not used tobacco or nicotine products Exclusion Criteria: * Has any respiratory disease (ex - asthma, COPD, etc...) * Has/had high blood pressure * Has/had liver disease * Has/had cancer * Has experience negative effects when vaped previously * Pregnant or nursing
Contact & Investigator
Stephen Hecht
PRINCIPAL INVESTIGATOR
University of Minnesota
Frequently Asked Questions
Who can join the NCT07134426 clinical trial?
This trial is open to participants of all sexes, aged 21 Years or older, studying Former Smoker. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07134426 currently recruiting?
Yes, NCT07134426 is actively recruiting participants. Contact the research team at alche003@umn.edu for enrollment information.
Where is the NCT07134426 trial being conducted?
This trial is being conducted at Minneapolis, United States.
Who is sponsoring the NCT07134426 clinical trial?
NCT07134426 is sponsored by University of Minnesota. The principal investigator is Stephen Hecht at University of Minnesota. The trial plans to enroll 100 participants.