NCT03832062 Value of Analysing Under-utilised Leftover Tissue (VauLT)
| NCT ID | NCT03832062 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Royal Marsden NHS Foundation Trust |
| Condition | Oncology |
| Study Type | OBSERVATIONAL |
| Enrollment | 800 participants |
| Start Date | 2018-09-10 |
| Primary Completion | 2028-08-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 800 participants in total. It began in 2018-09-10 with a primary completion date of 2028-08-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Intratumour heterogeneity is well recognized in multiple cancer types and ultimately leads to therapeutic resistance. It also limits the ability of small samples to represent the whole tumour, having implications for diagnosis, molecular analysis and understanding of the tumour immune microenvironment. By blending- 'homogenizing'- leftover tumour tissue in excess of that required for diagnosistic purposes, one may create a more representative sample for analysis.
Eligibility Criteria
Inclusion Criteria: 1. Leftover formalin-fixed tissue (ie that would be otherwise discarded by histopathology) from cancer surgery. 2. Tissues for Research consent has been provided. 3. Patient age \>18yo. 4. Minimum of 1 gram of residual tumour remaining in leftover surgical tissue 5. Minimum of 1 gram of normal tissue present. Exclusion Criteria: 1. Advanced Practitioner in histological dissection deems tumour sample to be inadequate. 2. Leftover surgical tumour tissue greater than 20kg.
Contact & Investigator
Samra Turajlic
STUDY CHAIR
Royal Marsden NHS Foundation Trust
Frequently Asked Questions
Who can join the NCT03832062 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Oncology. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT03832062 currently recruiting?
Yes, NCT03832062 is actively recruiting participants. Contact the research team at vault@rmh.nhs.uk for enrollment information.
Where is the NCT03832062 trial being conducted?
This trial is being conducted at London, United Kingdom.
Who is sponsoring the NCT03832062 clinical trial?
NCT03832062 is sponsored by Royal Marsden NHS Foundation Trust. The principal investigator is Samra Turajlic at Royal Marsden NHS Foundation Trust. The trial plans to enroll 800 participants.