NCT06983652 Validation of the Use of Terahertz Scanning System on Corneal Scars and Corneal Edema
| NCT ID | NCT06983652 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Singapore Eye Research Institute |
| Condition | Corneal Diseases |
| Study Type | OBSERVATIONAL |
| Enrollment | 150 participants |
| Start Date | 2024-07-01 |
| Primary Completion | 2026-06-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 150 participants in total. It began in 2024-07-01 with a primary completion date of 2026-06-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This observational study aims to validate the use of THz scanning system in corneal edema and corneal scars, and to investigate the accuracy and performance on the use of THz scanning system in the evaluation of the progression of corneal edema and corneal scars. Participants corneal scars and corneal edema will undergo THz scanning, followed by a series of conventional clinical examinations for detailed characterization of the corneal lesion. The performance of the use of THz system on corneal scars and edema will be evaluated by correlating measurements from the THz scans with those obtained from standard clinical methods. The investigators hypothesize that the THz scanning system has the capacity to evaluate the hydration level on human corneas.
Eligibility Criteria
Inclusion Criteria: * Be at least 21 years of age. * Regardless of gender (Male/Female). * Regardless of race (Chinese/Malay/Indian/Eurasian/Others). * Willingness and ability to follow all instructions and comply with study schedule for study visit. * Patients with corneal endothelial dysfunction (Fuchs' endothelial dystrophy or other causes of bullous keratopathy) at any disease stage OR Patients with corneal scars from any cause, with the absence of corneal edema. * Ability to hold face sufficiently stable to undergo necessary scans. Exclusion Criteria: * Eyes with active inflammation or infection, or chronic ocular surface inflammation * Unable to give consent * Physically immobile/poor instructional compliance * PI determined * Pregnant/ breast feeding women
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06983652 clinical trial?
This trial is open to participants of all sexes, aged 21 Years or older, studying Corneal Diseases. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06983652 currently recruiting?
Yes, NCT06983652 is actively recruiting participants. Contact the research team at liu.yu.chi@snec.com.sg for enrollment information.
Where is the NCT06983652 trial being conducted?
This trial is being conducted at Singapore, Singapore.
Who is sponsoring the NCT06983652 clinical trial?
NCT06983652 is sponsored by Singapore Eye Research Institute. The trial plans to enroll 150 participants.