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Recruiting NCT07331506

NCT07331506 Validation of the Oncoliq Test for the Early Detection of Breast Cancer.

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Clinical Trial Summary
NCT ID NCT07331506
Status Recruiting
Phase
Sponsor Oncoliq US Inc
Condition Breast Cancer Detection
Study Type OBSERVATIONAL
Enrollment 300 participants
Start Date 2025-10-17
Primary Completion 2026-02-28

Eligibility & Interventions

Sex Female only
Min Age 40 Years
Max Age 70 Years
Study Type OBSERVATIONAL
Interventions
Peripheral blood draw

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 300 participants in total. It began in 2025-10-17 with a primary completion date of 2026-02-28.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Cancer continues to be one of the most significant public health issues worldwide. Thanks to early detection, the mortality rate of certain types of cancer has decreased significantly. However, the lack of accessible, low-cost, non-invasive, non-toxic, and easy-to-implement diagnostic methods results in late diagnoses, leading to 1 in every 6 people dying from cancer today. MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression and are found both inside cells and in bodily fluids such as blood and urine. Several studies have demonstrated their role in human diseases, especially cancer, where tumors release miRNAs into the bloodstream that can be used as biomarkers for early detection. The research and development team at Oncoliq SAS identified a panel of miRNAs associated with breast cancer, with a detection performance of 82% sensitivity and 83% specificity, validated in exploratory and preliminary confirmatory studies. These results led to the filing of a patent based on liquid biopsy technology. The objective of this protocol is to establish a panel of miRNAs for the early detection of breast cancer using samples from breast cancer patients and a cancer-free control group. Validation of the miRNAs will be carried out through RT-qPCR. This stage constitutes the analytical validation of the biomarkers, with the goal of developing an algorithm capable of classifying individuals with and without breast cancer. In future stages, a pilot clinical trial is planned to evaluate test implementation and clinical validation.

Eligibility Criteria

Inclusion Criteria: Group 1 - Breast Cancer: Age between 40 and 70 years Diagnosis of breast cancer at any stage No prior surgical treatment No prior antineoplastic treatment Pathology report available at the time of enrollment Signed informed consent Group 2 - No Cancer (Control): Age between 50 and 70 years No diagnosis or personal history of any type of cancer Digital mammography and breast ultrasound showing no breast pathology (BI-RADS 1 or 2) Signed informed consent Exclusion Criteria: Refusal to sign the informed consent Communication issues that hinder understanding (hearing loss, blindness, intellectual disability, or dementia) Venipuncture for blood collection impracticable or posing a risk Personal history of previous cancer

Contact & Investigator

Central Contact

Adriana De Siervi, PhD in Molecular Biology

✉ adesiervi@oncoliq.bio

📞 +54 11 3269 5832

Frequently Asked Questions

Who can join the NCT07331506 clinical trial?

This trial is open to female participants only, aged 40 Years or older, up to 70 Years, studying Breast Cancer Detection. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT07331506 currently recruiting?

Yes, NCT07331506 is actively recruiting participants. Contact the research team at adesiervi@oncoliq.bio for enrollment information.

Where is the NCT07331506 trial being conducted?

This trial is being conducted at Buenos Aires, Argentina.

Who is sponsoring the NCT07331506 clinical trial?

NCT07331506 is sponsored by Oncoliq US Inc. The trial plans to enroll 300 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology