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Recruiting NCT05870020

Validation of a Quality of Life Assessment Tool in Adult Generalized Dystonodyskinetic Syndromes Treated by Continuous Electrical Neuromodulation

Trial Parameters

Condition Dystono-dyskinetic Syndromes
Sponsor University Hospital, Montpellier
Study Type INTERVENTIONAL
Phase N/A
Enrollment 146
Sex ALL
Min Age 18 Years
Max Age 80 Years
Start Date 2023-05-24
Completion 2026-10
Interventions
Questionnaire (DBS-QoLs)

Brief Summary

In spite of a growing interest in the evaluation of health-related quality of life in movement's disorders management, there is no tool specifically dedicated to dystonia and related syndromes that measures both the objective severity of the handicap and the patient's feelings about the surgical treatment in terms of subjective improvement. We have been working for several years at the bedside of patients operated on in the " pathologies cérébrales résistantes " Unit on the development of a related questionnaire to assess both the motor severity and the patients' feelings about the evolution of their disease under Deep Brain Stimulation (DBS). The self-questionnaire designed would allow to a certain extent to get away from the two gold standards currently used in the field, i.e. the Burke, Fahn \& Marsden Dystonia Rating Scale (BFMDRS) and the SF-36, thus facilitating the evaluation and allowing a homogenization of the practices for the different implanting centers on the french territory.

Eligibility Criteria

Inclusion Criteria: * Adulte between 18 an 80 years * Patient with a generalized dystono-dyskinetic syndrome treated by Electrical Neuromodulation Continue and follow-up in the unit * Subject affiliated to the French social security system Exclusion Criteria: * non-French speaker * patients who are physically unable to answer the questionnaire and who have no trusted person to help * severe cognitive impairment (MoCA \<10, MDRS \<123, PM-38 \<70) * lack of informed consent

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