| NCT ID | NCT07660250 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Washington University School of Medicine |
| Condition | Degenerative Cervical Myelopathy |
| Study Type | INTERVENTIONAL |
| Enrollment | 36 participants |
| Start Date | 2026-04-14 |
| Primary Completion | 2028-04 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 36 participants in total. It began in 2026-04-14 with a primary completion date of 2028-04.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The objective of this study is to generate preliminary data to establish the feasibility and effectiveness of transauricular vagus nerve stimulation (taVNS) to improve post-operative outcomes of moderate to severe degenerative cervical myelopathy (DCM)
Eligibility Criteria
Inclusion Criteria: * 18 years of age or older * Moderate or severe degenerative cervical myelopathy according to the mJOA * Decompression surgery planned Exclusion Criteria: * • Pregnancy * Electrically active implants (e.g. pacemaker) * Known diagnosis of amyotrophic lateral sclerosis, multiple sclerosis, rheumatoid arthritis, concomitant thoracic and/or lumbar stenosis, spine tumor, HIV-related myelopathy * Ongoing cancer therapy * Ongoing use of immunomodulating or suppressive medication * Sustained bradycardia with a heartrate \<50 beats per minute for \> 5 minutes following admission. * Prior cervical spine surgery
Contact & Investigator
Wilson Z Ray, MD
PRINCIPAL INVESTIGATOR
Washington University School of Medicine
Frequently Asked Questions
Who can join the NCT07660250 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Degenerative Cervical Myelopathy. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07660250 currently recruiting?
Yes, NCT07660250 is actively recruiting participants. Contact the research team at koesterl@wustl.edu for enrollment information.
Where is the NCT07660250 trial being conducted?
This trial is being conducted at St Louis, United States.
Who is sponsoring the NCT07660250 clinical trial?
NCT07660250 is sponsored by Washington University School of Medicine. The principal investigator is Wilson Z Ray, MD at Washington University School of Medicine. The trial plans to enroll 36 participants.