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Recruiting NCT06069973

NCT06069973 Using Machine Learning and Biomarkers for Early Detection of Delayed Cerebral Ischemia

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Clinical Trial Summary
NCT ID NCT06069973
Status Recruiting
Phase
Sponsor Sahlgrenska University Hospital
Condition Ischemic Stroke
Study Type OBSERVATIONAL
Enrollment 1,500 participants
Start Date 2024-01-01
Primary Completion 2033-12-31

Trial Parameters

Condition Ischemic Stroke
Sponsor Sahlgrenska University Hospital
Study Type OBSERVATIONAL
Phase N/A
Enrollment 1,500
Sex ALL
Min Age 18 Years
Max Age 110 Years
Start Date 2024-01-01
Completion 2033-12-31
Interventions
No intervention, observational study

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Brief Summary

The overall goal of this project is to determine if machine learning and analysis of neurospecific biomarkers can enable early detection of upcoming or ongoing cerebral ischaemia in patients suffering from subarachnoid haemorrhage with altered consciousness due to cerebral injury or sedation. Analyses of heart rate variability, electroencephalgraphy,nearinfrared spectroscopy, cerebral autoregulation, and brain injury specific biomarkers in blood and cerebrospinal fluid will be performed.

Eligibility Criteria

Inclusion Criteria: Patients over the age of 18 with aneurysmal subarachnoid hemorrhage admitted to intensive care units at Sahlgrenska University hospital. Exclusion Criteria: * Unable to consent, * Cardiac arrythmia, * Previous brain damage

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